Kumar Rohit, Issing Wolfgang
Department of Otolaryngology-Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK.
Case Rep Otolaryngol. 2011;2011:397451. doi: 10.1155/2011/397451. Epub 2011 Sep 15.
Objective. We report a rare and unusual case of bronchial carcinoma presenting with symptoms of complications of sinonasal disease. Case Report. A 66-year-old lady was referred with a 1-week history of progressive ocular pain, chemosis, and visual disturbance. Computed tomography of the paranasal sinuses revealed frontal and ethmoidal sinus opacification with orbital involvement consistent with a diagnosis of orbital cellulitis secondary to sinusitis. Surgical exploration revealed that the sinuses and right orbit were filled with soft tissue and subsequent histopathological examination of the biopsies indicating metastases from an adenosquamous bronchial carcinoma. Further imaging revealed a large, asymptomatic, bronchial primary with deposits in the brain and liver. The advanced presentation of the disease limited treatment to best supportive care. Conclusion. Orbital cellulitis and sinonasal malignancies have a similar pattern of clinical presentation, posing a potential diagnostic pitfall. There are only two previously reported cases of metastatic lung carcinoma in the frontal sinus with 15 cases of sinonasal tract involvement reported overall. There are no reported cases of adenosquamous carcinoma in the sinonasal tract.
目的。我们报告一例罕见且不寻常的支气管癌病例,其表现为鼻窦疾病并发症的症状。病例报告。一名66岁女性因进行性眼痛、球结膜水肿和视力障碍1周前来就诊。鼻窦计算机断层扫描显示额窦和筛窦混浊并累及眼眶,符合鼻窦炎继发眼眶蜂窝织炎的诊断。手术探查发现鼻窦和右眼眶充满软组织,随后对活检组织进行的组织病理学检查表明为腺鳞支气管癌转移。进一步影像学检查发现一个大的、无症状的支气管原发灶,并伴有脑和肝转移。疾病的晚期表现使治疗限于最佳支持治疗。结论。眼眶蜂窝织炎和鼻窦恶性肿瘤有相似的临床表现模式,存在潜在的诊断陷阱。此前仅有两例额窦转移性肺癌的报告,总体上有15例鼻窦受累的报告。尚无鼻窦腺鳞癌的报告病例。