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透析治疗第一年中不同的抑郁症状轨迹:与疾病认知的关联。

Distinct depression symptom trajectories over the first year of dialysis: associations with illness perceptions.

机构信息

Health Psychology Section, Psychology Department, Institute of Psychiatry, King's College London, UK.

出版信息

Ann Behav Med. 2013 Feb;45(1):78-88. doi: 10.1007/s12160-012-9410-5.

Abstract

BACKGROUND

Depression in the dialysis population is common, but trajectories of depression symptoms are unknown.

PURPOSE

This study aims to (1) examine whether different patterns of depression symptoms exist over the first year of dialysis and (2) to understand if illness perceptions are associated with observed trajectories of depression symptoms.

METHOD

Incident dialysis patients (n = 160) completed the Beck Depression Inventory II and the Revised Illness Perception Questionnaire soon after starting dialysis and again at 6 and 12 months. Latent class growth modelling identified distinct groups of depression symptom trajectories.

RESULTS

Three depression trajectories were identified: "low-reducing" (62 %), "moderate-increasing" (21.8 %) and "high-reducing" (16.2 %). Higher levels of depression were associated with a poorer understanding of the illness (coherence) and perceptions that kidney failure has severe consequences and a more cyclical timeline. Beliefs that treatment controlled kidney failure decreased over time in patients with increasing depression symptoms.

CONCLUSION

Distinct patterns of depression symptoms are associated with illness perceptions. The potential to identify common patterns of depression symptoms may help target treatments at those most likely to benefit.

摘要

背景

透析人群中抑郁很常见,但抑郁症状的发展轨迹尚不清楚。

目的

本研究旨在(1)考察透析开始后第一年是否存在不同模式的抑郁症状,以及(2)了解疾病认知是否与观察到的抑郁症状发展轨迹有关。

方法

160 名新进入透析的患者在开始透析后不久、6 个月和 12 个月时分别完成贝克抑郁量表第二版和修订后的疾病认知问卷。潜在类别增长模型确定了不同的抑郁症状轨迹群组。

结果

发现了三种抑郁轨迹:“低降低”(62%)、“中升高”(21.8%)和“高降低”(16.2%)。较高水平的抑郁与对疾病认知较差(一致性)以及对肾衰竭后果严重和更具周期性的时间线的看法有关。随着抑郁症状加重,患者对治疗控制肾衰竭的信念会随时间而降低。

结论

不同模式的抑郁症状与疾病认知有关。识别常见的抑郁症状模式可能有助于将治疗针对最有可能受益的人群。

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