Hodgman J E, Gonzalez F, Hoppenbrouwers T, Cabal L A
University of Southern California School of Medicine.
Am J Dis Child. 1990 Jan;144(1):54-7. doi: 10.1001/archpedi.1990.02150250064032.
The occurrence of central apnea of 15 seconds or longer, transient episodes of bradycardia (TEB), and periodic breathing were studied in 66 healthy premature infants when at least 1 week old and between 32 and 36 weeks postconceptual age. Eight-hour cardiorespiratory recordings were visually scanned for the presence of these patterns. Central apnea of 15 seconds or longer was seen in almost half of the infants. The TEB were numerous, and the majority were not associated with central apnea; however, all but five of the apneic episodes that lasted 15 seconds or longer were accompanied by a TEB. Infants spent as much as 40% of their time in periodic breathing. The frequency with which these patterns are seen in healthy premature infants strongly suggests that they are normal findings. Our results do not support the opinion that brief periods of apnea are abnormal when accompanied by a TEB.
对66名健康的早产婴儿进行了研究，这些婴儿出生至少1周，孕龄在32至36周之间，观察他们是否出现持续15秒或更长时间的中枢性呼吸暂停、短暂性心动过缓发作（TEB）和周期性呼吸。对8小时的心肺记录进行了肉眼扫描，以查找这些模式的存在情况。几乎一半的婴儿出现了持续15秒或更长时间的中枢性呼吸暂停。TEB很常见，且大多数与中枢性呼吸暂停无关；然而，持续15秒或更长时间的呼吸暂停发作中，除了5次外，其余均伴有一次TEB。婴儿有多达40%的时间处于周期性呼吸状态。在健康早产婴儿中观察到这些模式的频率强烈表明它们是正常表现。我们的结果不支持以下观点，即短暂的呼吸暂停伴有TEB时是异常的。
