Yılmaz Hava, Mutlu Yılmaz Esmeray, Esen Saban, Sünbül Mustafa, Leblebicioğlu Hakan
Ondokuz Mayıs University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, Turkey.
Mikrobiyol Bul. 2012 Jul;46(3):470-4.
Treatment of catheter-associated infections caused by Staphylococcus aureus is difficult without catheter removal, because of the biofilm formation and its high virulence. In this report, we presented our clinical and microbiological experience with systemic daptomycin (6 mg/kg/on alternate days IV) as well as antibiotic lock therapy (filling of the catheter lumen with 3.5 mg/ml daptomycin together with 0.045 mg/ml calcium) in the treatment of a catheter-associated bloodstream infection caused by methicillin-resistant S.aureus in a patient with hemodialysis catheter which could not be removed.
由于生物膜的形成及其高毒力,在不拔除导管的情况下,治疗由金黄色葡萄球菌引起的导管相关感染很困难。在本报告中,我们介绍了在一名无法拔除血液透析导管的患者中,使用全身用达托霉素(6毫克/千克/隔日静脉注射)以及抗生素封管疗法(用3.5毫克/毫升达托霉素与0.045毫克/毫升钙填充导管内腔)治疗耐甲氧西林金黄色葡萄球菌引起的导管相关血流感染的临床和微生物学经验。