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定期看牙医与口腔和咽喉癌的早期诊断有关。

Regular dental visits are associated with earlier stage at diagnosis for oral and pharyngeal cancer.

机构信息

Department of Epidemiology, Brown University, 70 Ship Street, Box G-E5, Providence, RI 02912, USA.

出版信息

Cancer Causes Control. 2012 Nov;23(11):1821-9. doi: 10.1007/s10552-012-0061-4. Epub 2012 Sep 8.

Abstract

PURPOSE

Oral and pharyngeal cancer patients diagnosed at an advanced stage experience increased morbidity and mortality relative to those with localized disease. The aim of this study was to assess the impact of dental insurance status and regularity of dental visits on early detection of oral and pharyngeal cancer.

METHODS

We examined the relationship of dental insurance and frequency of dental visits with stage at diagnosis among 441 oral and pharyngeal cancer cases from a population-based study of head and neck cancer. Ordinal logistic regression models were used to assess the association with stage, and tumor (T) and nodal (N) classification.

RESULTS

Never or rarely going to the dentist was associated with being diagnosed at higher stage for oral and pharyngeal cancer (cumulative OR = 2.28, 95 % CI: 1.02-5.10) and oral cancer (cumulative OR = 9.17, 95 % CI: 2.70-31.15) compared to those going to the dentist at least annually. Oral and pharyngeal cancer patients who went to the dentist infrequently (cumulative OR = 1.82, 95 % CI: 1.09-3.05) or rarely/never (cumulative OR = 3.24, 95 % CI: 1.59-6.57) were diagnosed with a higher T classification compared with those who went at least annually.

CONCLUSIONS

Receipt of regular dental examinations at least annually may reduce the public health burden of oral and pharyngeal cancer by facilitating earlier detection of the disease.

摘要

目的

与局限性疾病患者相比,诊断为晚期的口腔和咽部癌症患者的发病率和死亡率更高。本研究旨在评估牙科保险状况和定期看牙医对口腔和咽部癌症早期发现的影响。

方法

我们检查了牙科保险和看牙医的频率与 441 例来自头颈癌人群基础研究的口腔和咽部癌症病例的诊断阶段之间的关系。使用有序逻辑回归模型评估与阶段以及肿瘤(T)和淋巴结(N)分类的相关性。

结果

从不或很少去看牙医与口腔和咽部癌症(累积 OR = 2.28,95 % CI:1.02-5.10)和口腔癌(累积 OR = 9.17,95 % CI:2.70-31.15)的诊断阶段较高相关,与至少每年去看牙医的患者相比。口腔和咽部癌症患者很少或从未去看牙医(累积 OR = 1.82,95 % CI:1.09-3.05)或很少/从未去看牙医(累积 OR = 3.24,95 % CI:1.59-6.57)与至少每年去看牙医的患者相比,T 分类诊断较高。

结论

至少每年定期进行牙科检查可能会通过更早发现疾病,从而减轻口腔和咽部癌症的公共卫生负担。

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