老年患者骶神经刺激的成功率、生活质量及可行性：1年随访
Success rates, quality of life, and feasibility of sacral nerve stimulation in elderly patients: 1-year follow-up.
作者信息
Angioli Roberto, Montera Roberto, Plotti Francesco, Aloisi Alessia, Montone Eva, Zullo Marzio Angelo
机构信息
Department of Obstetrics and Gynaecology, University of Rome Campus Bio-Medico, Via Álvaro del Portillo, 200, 00128, Rome, Italy.
出版信息
Int Urogynecol J. 2013 May;24(5):789-94. doi: 10.1007/s00192-012-1928-3. Epub 2012 Sep 8.
INTRODUCTION AND HYPOTHESIS
Urgency urinary incontinence (UUI) frequently occurs in elderly. International guidelines recommend pharmacological therapy as first-line treatment, but elderly do not respond in many cases. The purpose of this study was to report cure rates, quality of life, and feasibility of sacral neurostimulation (SNS) as an alternative option in the elderly.
MATERIALS AND METHODS
From October 2008 to April 2010, women >65 years with UUI who were refractory to pharmacological treatments were enrolled in this study and underwent SNS. At 12 months after surgery, patients were asked to compile a 3-day voiding diary and a urogynecologic standardized questionnaire: the Overactive Bladder Questionnaire (OAB-q).
RESULTS
Eighteen patients met our inclusion criteria. Fifteen (83.3 %) underwent implantation of the neuromodulator. Twelve months after surgery, an overall success rate of 83.3 % was registered. A statistically significant difference (P<0.0001) between baseline and postsurgery OAB-q scores was recorded.
CONCLUSIONS
SNS can be considered an alternative treatment for UUI in older women.
引言与假设
急迫性尿失禁（UUI）在老年人中频繁发生。国际指南推荐药物治疗作为一线治疗方法，但在许多情况下老年人对此并无反应。本研究的目的是报告骶神经刺激（SNS）作为老年患者替代治疗方案的治愈率、生活质量及可行性。
材料与方法
2008年10月至2010年4月，年龄大于65岁、对药物治疗无效的UUI女性纳入本研究并接受SNS治疗。术后12个月，要求患者填写一份3天排尿日记及一份泌尿妇科标准化问卷：膀胱过度活动症问卷（OAB-q）。
结果
18例患者符合纳入标准。15例（83.3%）接受了神经调节装置植入。术后12个月，总体成功率为83.3%。记录到术前与术后OAB-q评分之间存在统计学显著差异（P<0.0001）。
结论
SNS可被视为老年女性UUI的一种替代治疗方法。
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