Section of Internal Medicine, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Emerg Med J. 2013 Aug;30(8):650-6. doi: 10.1136/emermed-2012-201235. Epub 2012 Sep 8.
(1) Validate an existing clinical tool for assessing risk after deliberate self-harm (DSH), Manchester Self-Harm Rule, in a new setting and new population, (2) develop a clinical decision rule based on factors associated with repeated self-harm in a Swedish population and (3) compare these rules.
A consecutive series of 1524 patients attending one of Scandinavia's largest emergency departments (ED) due to DSH during a 3-year period were included. Explanatory factors were collected from hospital charts and national databases. A nationwide register-based follow-up of new DSH episode or death by suicide within 6 months was used. We used logistic regression, area under the curve and classification trees to identify factors associated with repetition. To evaluate the ability of different decision rules to identify patients who will repeat DSH, we calculated the sensitivity and specificity.
Repeated DSH or suicide within 6 months.
The cumulative incidence for patients repeating within 6 months was 20.3% (95% CI 18.0% to 22.0%). Application of Manchester Self-Harm Rule to our material yielded a sensitivity of 89% and a specificity of 21%. The clinical decision rule based on four factors associated with repetition in the Swedish population yielded a sensitivity of 90% and a specificity of 18%.
Application of either rules, with high sensitivity, may facilitate assessment in the ED and help focus right resources on patients at a higher risk. Irrespective of the choice of decision rule, it is difficult to separate those who will repeat from those who will not due to low specificity.
(1)在新环境和新人群中验证用于评估故意自伤(DSH)后风险的现有临床工具(曼彻斯特自伤规则),(2)基于与瑞典人群中重复自伤相关的因素开发临床决策规则,(3)比较这些规则。
在 3 年期间,连续纳入 1524 名因 DSH 就诊于斯堪的纳维亚最大急诊部之一的患者。解释性因素从病历和国家数据库中收集。使用全国范围内基于登记的随访,以确定 6 个月内新 DSH 发作或自杀死亡的情况。我们使用逻辑回归、曲线下面积和分类树来确定与重复相关的因素。为了评估不同决策规则识别将重复 DSH 的患者的能力,我们计算了敏感性和特异性。
6 个月内重复 DSH 或自杀。
6 个月内重复的患者累积发生率为 20.3%(95%CI 18.0%至 22.0%)。曼彻斯特自伤规则在我们的材料中的应用敏感性为 89%,特异性为 21%。基于与瑞典人群中重复相关的四个因素的临床决策规则的敏感性为 90%,特异性为 18%。
无论选择哪种决策规则,由于特异性较低,都很难将那些将重复的患者与那些不会重复的患者区分开来。应用这两种规则都具有较高的敏感性,可能有助于在急诊室进行评估,并有助于将正确的资源集中在风险较高的患者身上。