Department of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA.
J Clin Endocrinol Metab. 2012 Sep;97(9):2957-68. doi: 10.1210/jc.2011-2744.
Hirsutism is a common endocrinological complaint. The causes of this complaint can vary from dissatisfaction with a normal pattern of hair growth on the one hand, to the first clinical manifestation of androgen overproduction by an adrenal adenocarcinoma on the other. The purpose of this short review is to reexamine the physiology of hair growth in normal women, identify the common abnormal patterns, and explore the differential diagnosis associated with each. An approach to working through the differential diagnosis will be described, and the commonly available treatment modalities for the various forms of hirsutism will be examined in terms of risk and benefit. The review is written from the point of view of the physician and the most efficient, cost effective, and safe clinical approach to the patient with the problem.
多毛症是一种常见的内分泌疾病。其病因多种多样,从一方面对正常毛发模式的不满,到另一方面肾上腺腺癌引起的雄激素过多的最初临床表现。本次简短综述的目的是重新审视正常女性的毛发生长生理学,确定常见的异常模式,并探讨与每种模式相关的鉴别诊断。本文将描述一种鉴别诊断方法,并根据风险和获益评估各种多毛症的常用治疗方法。本文从医生的角度出发,探讨了针对该问题患者最有效、最具成本效益和最安全的临床方法。