Department of Obstetrics and Gynaecology, CHU Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
Maturitas. 2012 Oct;73(2):164-6. doi: 10.1016/j.maturitas.2012.06.014. Epub 2012 Sep 7.
The decision to perform an elective bilateral salpingo-oophorectomy (BSO) at the time of a hysterectomy for a benign condition is complex.
To assess the determinants of the decision to proceed to a prophylactic BSO during a hysterectomy for a benign condition.
We collected demographic and clinical data, including age, menopausal status and risk of ovarian cancer. Using a regression model we analysed the decision perform a prophylactic BSO in women successively admitted for a hysterectomy for a benign condition, in relation to the collected demographic and clinical data.
Data were collected for 43 women, aged between 37 and 65 years (mean age 48.6 years, SD 6.9), on the day before their hysterectomy. Thirty-six (84%) had a total hysterectomy and 7 (16%) a subtotal hysterectomy; 40 (93%) had a laparoscopic procedure. Prophylactic BSO was significantly associated with age: none of the women aged under 40 years had the procedure, compared with 8% of those aged 41-45 years, 29% of those aged 46-50 years and 83% of those aged 51 years or more (χ(2)=23; P<0.001). Of the postmenopausal women, 67% had a prophylactic BSO, compared with 24% of the premenopausal women (χ(2)=6; P<0.047). In this small series of patients no relationship was found between the decision to perform a BSO and the risk of ovarian cancer. Age was the only significant variable in the regression model (pseudo R(2) Nagelkerke=0.6, P<0.05).
The physician's recommendation to perform an elective BSO at the time of a hysterectomy for a benign condition is strongly influenced by the patients' age.
在因良性疾病行子宫切除术时决定行预防性双侧输卵管卵巢切除术（BSO）是复杂的。
评估在因良性疾病行子宫切除术时决定行预防性 BSO 的决定因素。
我们收集了人口统计学和临床数据，包括年龄、绝经状态和卵巢癌风险。使用回归模型，我们分析了在因良性疾病连续入院行子宫切除术的女性中，与收集的人口统计学和临床数据相关的行预防性 BSO 的决定。
在子宫切除术前一天收集了 43 名年龄在 37 至 65 岁之间（平均年龄 48.6 岁，标准差 6.9）的女性的数据。36 名（84%）行全子宫切除术，7 名（16%）行次全子宫切除术；40 名（93%）行腹腔镜手术。预防性 BSO 与年龄显著相关：40 岁以下的女性无一例行该手术，而 41-45 岁的女性为 8%，46-50 岁的女性为 29%，51 岁及以上的女性为 83%（χ²=23；P<0.001）。绝经后的女性中，67%行预防性 BSO，而绝经前的女性中，这一比例为 24%（χ²=6；P<0.047）。在这个小系列患者中，BSO 决策与卵巢癌风险之间没有发现关系。年龄是回归模型中唯一具有统计学意义的变量（假 R²Nagelkerke=0.6，P<0.05）。
在因良性疾病行子宫切除术时，医生建议行选择性 BSO 强烈受到患者年龄的影响。
