Dong S, Hu Y S, Du W, Tao W, Zhang X H, Zhuang P, Li Y J
Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
J Int Med Res. 2012;40(4):1499-506. doi: 10.1177/147323001204000429.
This study investigated spontaneous dorsal horn potentials in patients with pain after brachial plexus avulsion and determined the effect of dorsal root entry zone (DREZ) lesioning on these potentials and on pain levels.
Electrospinography (ESG) recordings were undertaken in seven patients using a noninvasive electrocorticography strip electrode. Measurements were taken from the DREZ on the intact side of the spinal cord before lesioning of the injured DREZ and from the injured DREZ before and after lesioning.
DREZ lesioning had a significant positive effect on pain at 12 months postoperatively. At 15.0 Hz, the mean ESG power from the injured DREZ before lesioning was significantly higher than that from the intact DREZ. In addition, the mean ESG power from the injured DREZ after successful DREZ lesioning was significantly lower than that from the intact DREZ and that from the injured DREZ before lesioning.
The ESG power from the injured DREZ increases in patients with pain after brachial plexus avulsion compared with that of the intact DREZ; this increase is reduced by successful DREZ lesioning.
本研究调查了臂丛神经撕脱伤后疼痛患者的脊髓背角自发电位，并确定了背根入髓区（DREZ）毁损对这些电位及疼痛程度的影响。
使用非侵入性皮层脑电图带状电极对7例患者进行了电脊髓图（ESG）记录。在损伤侧DREZ毁损前，从脊髓完整侧的DREZ进行测量，并在毁损前后从损伤侧DREZ进行测量。
DREZ毁损在术后12个月时对疼痛有显著的积极影响。在15.0Hz时，毁损前损伤侧DREZ的平均ESG功率显著高于完整侧DREZ。此外，成功进行DREZ毁损后，损伤侧DREZ的平均ESG功率显著低于完整侧DREZ以及毁损前的损伤侧DREZ。
与完整侧DREZ相比，臂丛神经撕脱伤后疼痛患者损伤侧DREZ的ESG功率增加；成功进行DREZ毁损可降低这种增加。
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