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缩短急性中风患者住院时间的服务。

Services for reducing duration of hospital care for acute stroke patients.

作者信息

Fearon Patricia, Langhorne Peter

机构信息

Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, UK.

出版信息

Cochrane Database Syst Rev. 2012 Sep 12(9):CD000443. doi: 10.1002/14651858.CD000443.pub3.

Abstract

BACKGROUND

Stroke patients conventionally receive a substantial part of their rehabilitation in hospital. Services have now been developed which offer patients in hospital an early discharge with rehabilitation at home (early supported discharge (ESD)).

OBJECTIVES

To establish the effects and costs of ESD services compared with conventional services.

SEARCH METHODS

We searched the trials registers of the Cochrane Stroke Group (January 2012) and the Cochrane Effective Practice and Organisation of Care (EPOC) Group, MEDLINE (2008 to 7 February 2012), EMBASE (2008 to 7 February 2012) and CINAHL (1982 to 7 February 2012). In an effort to identify further published, unpublished and ongoing trials we searched 17 trial registers (February 2012), performed citation tracking of included studies, checked reference lists of relevant articles and contacted trialists.

SELECTION CRITERIA

Randomised controlled trials recruiting stroke patients in hospital to receive either conventional care or any service intervention which has provided rehabilitation and support in a community setting with an aim of reducing the duration of hospital care.

DATA COLLECTION AND ANALYSIS

The primary patient outcome was the composite end-point of death or long-term dependency recorded at the end of scheduled follow-up. Two review authors scrutinised trials and categorised them on their eligibility. We then sought standardised individual patient data from the primary trialists. We analysed the results for all trials and for subgroups of patients and services, in particular whether the intervention was provided by a co-ordinated multidisciplinary team (co-ordinated ESD team) or not.

MAIN RESULTS

Outcome data are currently available for 14 trials (1957 patients). Patients tended to be a selected elderly group with moderate disability. The ESD group showed significant reductions (P < 0.0001) in the length of hospital stay equivalent to approximately seven days. Overall, the odds ratios (OR) (95% confidence interval (CI)) for death, death or institutionalisation, death or dependency at the end of scheduled follow-up were OR 0.91 (95% CI 0.67 to 1.25, P = 0.58), OR 0.78 (95% CI 0.61 to 1.00, P = 0.05) and OR 0.80 (95% CI 0.67 to 0.97, P = 0.02) respectively. The greatest benefits were seen in the trials evaluating a co-ordinated ESD team and in stroke patients with mild to moderate disability. Improvements were also seen in patients' extended activities of daily living scores (standardised mean difference 0.12, 95% CI 0.00 to 0.25, P = 0.05) and satisfaction with services (OR 1.60, 95% CI 1.08 to 2.38, P = 0.02) but no statistically significant differences were seen in carers' subjective health status, mood or satisfaction with services. The apparent benefits were no longer statistically significant at five-year follow-up.

AUTHORS' CONCLUSIONS: Appropriately resourced ESD services provided for a selected group of stroke patients can reduce long-term dependency and admission to institutional care as well as reducing the length of hospital stay. We observed no adverse impact on the mood or subjective health status of patients or carers.

摘要

背景

中风患者传统上在医院接受大部分康复治疗。现在已开发出一些服务,可为住院患者提供早期出院并在家中进行康复治疗(早期支持出院(ESD))。

目的

确定与传统服务相比,早期支持出院服务的效果和成本。

检索方法

我们检索了Cochrane中风小组试验注册库(2012年1月)、Cochrane有效实践与护理组织(EPOC)小组试验注册库、MEDLINE(2008年至2012年2月7日)、EMBASE(2008年至2012年2月7日)和CINAHL(1982年至2012年2月7日)。为了识别更多已发表、未发表和正在进行的试验,我们检索了17个试验注册库(2012年2月),对纳入研究进行了引文追踪,检查了相关文章的参考文献列表并联系了试验者。

选择标准

随机对照试验,招募住院中风患者接受传统护理或任何在社区环境中提供康复和支持以减少住院时间的服务干预措施。

数据收集与分析

主要患者结局是在预定随访结束时记录的死亡或长期依赖的复合终点。两位综述作者仔细审查试验并根据其合格性对试验进行分类。然后我们向主要试验者索取标准化的个体患者数据。我们分析了所有试验以及患者和服务亚组的结果,特别是干预措施是否由协调的多学科团队(协调的早期支持出院团队)提供。

主要结果

目前有14项试验(1957例患者)的结局数据。患者倾向于为有中度残疾的特定老年群体。早期支持出院组的住院时间显著缩短(P<0.0001),相当于约7天。总体而言,在预定随访结束时,死亡、死亡或入住机构、死亡或依赖的比值比(OR)(95%置信区间(CI))分别为OR 0.91(95%CI 0.67至1.25,P = 0.58)、OR 0.78(95%CI 0.61至1.00,P = 0.05)和OR 0.80(95%CI 0.67至0.97,P = 0.02)。在评估协调的早期支持出院团队的试验以及轻度至中度残疾的中风患者中观察到最大益处。患者的日常生活扩展活动评分(标准化均数差0.12,95%CI 0.00至0.25,P = 0.05)和对服务的满意度(OR 1.60,95%CI 1.08至2.38,P = 0.02)也有改善,但在照顾者的主观健康状况、情绪或对服务的满意度方面未观察到统计学上的显著差异。在五年随访时,明显的益处不再具有统计学意义。

作者结论

为特定中风患者群体提供资源充足的早期支持出院服务可减少长期依赖和入住机构护理,同时缩短住院时间。我们未观察到对患者或照顾者的情绪或主观健康状况有不利影响。

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