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对肝硬化肝移植候选患者的超声心动图研究。

Echocardiographic study in cirrhotic patient candidates for liver transplantation.

作者信息

Espinosa M-D, Nogueras F, Olmedo C, Macias R, Muffak-Granero K, Comino A, Villegas T, Ramirez J-A, Garrote D, De Teresa J, Bueno P, Ferrón J-A

机构信息

Hepatology Unit, Digestive Service, Virgen de las Nieves University Hospital, Granada, Spain.

出版信息

Transplant Proc. 2012 Sep;44(7):2074-5. doi: 10.1016/j.transproceed.2012.07.078.

Abstract

We studied 81 cirrhotic patients who were candidates for liver transplantation to evaluate frequently detected cardiac alterations by echocardiographic study. Patients were distributed into three groups: group 1 comprised alcoholic cirrhotic patients (n = 40); group 2, viral cirrhotic patients (hepatitis C or B virus) (n = 35); and group 3, patients with primary biliary cirrhosis (n = 6). Cardiac chambers and diastolic functions were estimated by two-dimensional transthoracic echocardiography in M mode and Doppler. The most frequently detected cardiac structural alterations were left atrial diameter enlargement in 100% of the women and 40% of the men in group 1; 87.5% of the women and 15.4% of the men in group 2; and 33.3% of the women in group 3. Interventricular wall thickness enlargement in 50% of the women and 27.8% of the men in group 1, 25% of the women and 30.8% of the men in group 2, and 16.4% of the women in group 3. The prevalence of diastolic dysfunction was 45% in group 1, 32.3% in group 2, and 16.4% in group 3 (P > .05). There were no significant differences between the groups in cardiac chamber dimensions, left ventricular wall thickness, or prevalence of diastolic dysfunction.

摘要

我们研究了81例拟进行肝移植的肝硬化患者,通过超声心动图研究评估常见的心脏改变。患者被分为三组:第1组为酒精性肝硬化患者(n = 40);第2组为病毒性肝硬化患者(丙型或乙型肝炎病毒)(n = 35);第3组为原发性胆汁性肝硬化患者(n = 6)。采用二维经胸超声心动图的M型和多普勒模式评估心脏腔室和舒张功能。最常检测到的心脏结构改变为:第1组中100%的女性和40%的男性左心房直径增大;第2组中87.5%的女性和15.4%的男性左心房直径增大;第3组中33.3%的女性左心房直径增大。第1组中50%的女性和27.8%的男性室间隔增厚;第2组中25%的女性和30.8%的男性室间隔增厚;第3组中16.4%的女性室间隔增厚。舒张功能障碍的患病率在第1组为45%,第2组为32.3%,第3组为16.4%(P > .05)。各组在心脏腔室大小、左心室壁厚度或舒张功能障碍患病率方面无显著差异。

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