Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Dig Dis Sci. 2013 Mar;58(3):858-64. doi: 10.1007/s10620-012-2385-z. Epub 2012 Sep 14.
Double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreaticography (DBE-ERCP) is an effective method for interventions in the pancreaticobiliary system in the post-surgical patient. However, use of currently available endoscopic accessories during this procedure is limited due of the length of the conventional instrument (200 cm). The aim of this study was to explore the utility of the short DBE (152 cm) for the management of pancreaticobiliary disorders in patients with surgically altered anatomies.
Data were collected retrospectively on patients with various anatomic variations in whom ERCP was performed using the short DBE from April 2008 to November 2011. Basic demographic information, clinical presentation, preoperative imaging, and type of surgery, procedural technical success rate, and adverse events were evaluated. Descriptive analysis was used to document the demographic and clinical data of the patients.
We identified 79 patients in whom DBE-ERCP was attempted (38 % male, mean age 58 years). Indications for the procedure were removal of a previously placed stent (n = 5), suspected sphincter of Oddi dysfunction type 1 (n = 3), surgical biliary leak (n = 3), pancreatic anastomotic stricture (n = 2), suspected biliary stones (n = 48), and biliary strictures visualized on imaging (n = 18). Overall, the success rate of DBE-ERCP in all patients was 81 % (64/79). The scope could not reach the papilla or surgical anastomosis in 8 cases and duct cannulation failed in 7 cases. The following interventions were performed: biliary sphincterotomy (n = 39), dilation of CBD stenosis with a balloon (n = 30), biliary stent insertion (n = 25), stone removal (n = 35), brushing cytology of biliary strictures (n = 3), and stent retrieval (n = 4). Three patients developed post-procedure pancreatitis. There was 1 episode of self-limited bleeding.
The current study demonstrates that DBE assisted ERCP for pancreaticobiliary interventions using a short enteroscope are feasible in patients with surgically altered anatomy.
双气囊内镜辅助下内镜逆行胰胆管造影术(DBE-ERCP)是一种治疗外科术后患者胰胆系统疾病的有效方法。然而,由于常规器械的长度(200cm)限制,目前可用的内镜附件在该手术中的应用有限。本研究旨在探讨短型 DBE(152cm)在处理外科手术改变解剖结构患者的胰胆疾病中的应用价值。
我们回顾性收集了 2008 年 4 月至 2011 年 11 月期间使用短型 DBE 进行 ERCP 的各种解剖变异患者的数据。评估了基本人口统计学信息、临床表现、术前影像学和手术类型、程序技术成功率和不良事件。描述性分析用于记录患者的人口统计学和临床数据。
我们共纳入 79 例接受 DBE-ERCP 的患者(38%为男性,平均年龄 58 岁)。该操作的适应证包括:先前放置的支架取出(n=5)、疑似 1 型Oddi 括约肌功能障碍(n=3)、外科性胆漏(n=3)、胰吻合口狭窄(n=2)、疑似胆石(n=48)和影像学可见的胆管狭窄(n=18)。总体而言,所有患者的 DBE-ERCP 成功率为 81%(64/79)。8 例患者内镜无法到达乳头或外科吻合口,7 例患者胆管插管失败。以下介入治疗措施得以实施:胆管括约肌切开术(n=39)、CBD 狭窄球囊扩张术(n=30)、胆管支架置入术(n=25)、结石取出术(n=35)、胆管狭窄刷检细胞学检查(n=3)和支架取出术(n=4)。3 例患者术后发生胰腺炎,1 例患者出现自限性出血。
本研究表明,在外科手术改变解剖结构的患者中,使用短型内镜辅助下 DBE 进行胰胆介入治疗是可行的。