Institute of Horticulture, Zhejiang Academy of Agricultural Science, Hangzhou 310021, China.
Int J Biol Macromol. 2012 Dec;51(5):1140-6. doi: 10.1016/j.ijbiomac.2012.09.002. Epub 2012 Sep 12.
Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by the combination of chemical and instrumental analysis methods. The studies to evaluate the antioxidant potential and the hepatoprotective effects of the three polysaccharides showed that they had different activities in different evaluation system. HEP80 showed strong activity on antioxidant in vitro and potent hepatoprotective effect in vivo and the hepatoprotective effect may be due to its potent antioxidant capacity. The HEP could be exploited as antioxidant product and a supplement in the prevention of hepatic diseases. The study also opens an avenue for the efficient utilization of tofu whey, which is usually discarded in environment, causing concerns.
从在豆腐乳清上生长的珊瑚菌菌丝体中获得三种多糖级分，通过不同浓度乙醇的分级沉淀（HEP40、HEP60 和 HEP80）得到。通过化学和仪器分析方法的组合，研究了这三种粗多糖的化学和物理特性。评估三种多糖的抗氧化潜力和保肝作用的研究表明，它们在不同的评价体系中具有不同的活性。HEP80 在体外具有很强的抗氧化活性，在体内具有很强的保肝作用，其保肝作用可能与其很强的抗氧化能力有关。珊瑚菌可作为抗氧化产品和预防肝脏疾病的补充剂加以开发。该研究还为有效利用豆腐乳清开辟了途径，豆腐乳清通常被丢弃在环境中，引起了人们的关注。
