Department of Neonatal and Pediatric Intensive Care Unit, Klinikum Duisburg, Zu den Rehwiesen 9, 47055 Duisburg, Germany.
Neuroradiology. 2013 Feb;55(2):213-6. doi: 10.1007/s00234-012-1088-7. Epub 2012 Sep 15.
This study reports the first cases of neurogenic stunned myocardium in two children with vein of Galen aneurysmal malformation after interventional treatment.
Two newborns with vein of Galen aneurysmal malformation and high output cardiac failure developed a severe reversible left ventricular dysfunction shortly after embolization, concurrently with acute hydrocephalus.
There was a resolution of the cardiac symptoms of left ventricular dysfunction within a few days under treatment with milrinone and dobutamine.
Reversible left ventricular dysfunction is observed in adult patients mainly after subarachnoid hemorrhage and is called neurogenic stunned myocardium (NSM). Other forms of brain injuries have also been identified accounting for this condition in adults. In pediatric population especially with specific cerebral diseases, NSM may be underdiagnosed.
本研究报告了两例动静脉血管畸形患儿在介入治疗后的首例神经源性心肌顿抑病例。
两名患有动静脉血管畸形和高心输出量心力衰竭的新生儿在栓塞后不久并发急性脑积水,出现严重可逆性左心室功能障碍。
在米力农和多巴酚丁胺治疗下,左心室功能障碍的心脏症状在几天内得到缓解。
在成人患者中,主要在蛛网膜下腔出血后观察到可逆性左心室功能障碍,称为神经源性心肌顿抑(NSM)。其他形式的脑损伤也被认为与成人的这种情况有关。在儿科人群中,特别是在有特定脑部疾病的情况下,NSM 可能被漏诊。