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一期前路清创、植骨融合内固定治疗下颈椎结核伴后凸畸形的远期疗效

Long-term outcomes of one-stage anterior debridement, bone grafting, and internal fixation for the treatment of lower cervical tuberculosis with kyphosis.

作者信息

Mao Ningfang, Shi Zhicai, Ni Haijian, Zhao Yingchuan, Tang Hao, Liu Deding, Zhu Xiaodong, Bai Yushu, Li Ming

机构信息

Department of Orthopaedics, Changhai Hospital, Second Military Medical University, Shanghai, China.

出版信息

Br J Neurosurg. 2013 Apr;27(2):160-6. doi: 10.3109/02688697.2012.722706. Epub 2012 Sep 17.

Abstract

BACKGROUND

Patients with spinal deformities and nerve compression due to spinal tuberculosis often require surgical intervention. The objective of this study was to assess the long-term therapeutic effectiveness of one-stage anterior debridement, bone grafting, and internal fixation for lower cervical tuberculosis with kyphosis.

METHODS

Twenty-one patients with lower cervical tuberculosis and cervical kyphosis received one-stage anterior debridement, autologous iliac bone grafting, and internal plate fixation. Patients were followed-up postoperatively for at least 5 years. Outcome measures included neck pain using Visual Analogue Scale (VAS) scores, Frankel classification of spinal cord injury, and Cobb angle of cervical kyphosis.

RESULTS

Eighteen patients had lesions in 2 vertebrae and 3 had lesions in 3 vertebrae. Cervical tuberculosis was cured in all patients. The mean preoperative VAS score for neck pain was 8 (range: 6-10), whereas the mean best postoperative VAS score was 0.6 (range: 0-3). Mean final VAS score was significantly higher than the best VAS score (2.14 vs. 0.62). Of the 13 patients with symptoms of spinal cord compression, 9 improved by 1 grade and 4 improved by 2 grades according to Frankel classification at final follow-up. The mean preoperative Cobb angle of cervical kyphosis was 29° (range: 15°-50°), whereas the mean postoperative Cobb angle at final follow-up was -1.8° (range: 2-7°).

CONCLUSIONS

One-stage anterior debridement, bone grafting, and internal fixation can effectively remove lesions, decompress the nerve, reduce pain, and correct kyphosis in patients with cervical tuberculosis and associated kyphosis. Long-term postoperative outcomes were satisfactory.

摘要

背景

因脊柱结核导致脊柱畸形和神经受压的患者通常需要手术干预。本研究的目的是评估一期前路清创、植骨和内固定治疗下颈椎结核伴后凸畸形的长期治疗效果。

方法

21例下颈椎结核伴颈椎后凸畸形患者接受了一期前路清创、自体髂骨植骨和钢板内固定。术后对患者进行至少5年的随访。观察指标包括采用视觉模拟评分法(VAS)评估颈部疼痛、脊髓损伤的Frankel分级以及颈椎后凸的Cobb角。

结果

18例患者病变累及2个椎体,3例患者病变累及3个椎体。所有患者的颈椎结核均治愈。术前颈部疼痛的平均VAS评分为8分(范围:6 - 10分),而术后最佳平均VAS评分为0.6分(范围:0 - 3分)。最终平均VAS评分显著高于最佳VAS评分(2.14对0.62)。在13例有脊髓受压症状的患者中,末次随访时根据Frankel分级,9例改善1级,4例改善2级。术前颈椎后凸的平均Cobb角为29°(范围:15° - 50°),而末次随访时术后平均Cobb角为 - 1.8°(范围:2 - 7°)。

结论

一期前路清创、植骨和内固定可有效清除病灶、解除神经压迫、减轻疼痛并矫正颈椎结核伴后凸畸形患者的后凸畸形。术后长期效果满意。

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