Beatson Oncology Centre, Glasgow, UK.
Curr Oncol Rep. 2012 Dec;14(6):519-26. doi: 10.1007/s11912-012-0275-3.
Brachytherapy is an essential part of radiotherapy treatment for cervical cancer. Over the decades, it has evolved from manual loading of radium and caesium to remote after-loaders and from low-dose and medium-dose rates to high-dose rates. Over the past 10 years, 3D image-based Brachytherapy has evolved and established itself as the gold standard, improving local control and overall survival, and significantly reducing toxicity. In this article, we review some of the available literature on gynaecologic brachytherapy, more specifically on topics such as dose rates, high-dose-rate/pulsed-dose-rate (HDR/PDR) brachytherapy and image-based brachytherapy (IBBT), and present some of the evidence that establishes IBBT.
近距离放射治疗是宫颈癌放射治疗的重要组成部分。几十年来，它已经从镭和铯的手动加载发展到远程后加载，从低剂量和中剂量率发展到高剂量率。在过去的 10 年中，基于 3D 图像的近距离放射治疗已经发展并确立了自己的黄金标准，提高了局部控制率和总生存率，并显著降低了毒性。本文回顾了一些关于妇科近距离放射治疗的文献，特别是关于剂量率、高剂量率/脉冲剂量率（HDR/PDR）近距离放射治疗和基于图像的近距离放射治疗（IBBT）等主题，并介绍了一些确立 IBBT 的证据。
