Hippocampus. 2012 Oct;22(10):1952-64. doi: 10.1002/hipo.22064.
I review seven models of the contribution of perirhinal cortex (PRC) or neighboring neocortical regions to cognition. Five of the models address recognition memory function (Sohal and Hasselmo (2000) Network 11:169-190; Bogacz et al. (2001) J Comput Neurosci 10:5-23; Bogacz and Brown (2003a) Neurocomputing 52:1-6; Norman and O'Reilly (2003) Psychol Rev 110:611-646; Cowell et al. (2006) J Neurosci 26:12186-12197) and two account for the role of PRC in visual discrimination learning (Bussey and Saksida (2002) Eur J Neurosci 15:355-364; Cowell et al. (2010b) J Cogn Neurosci 22:2460-2479). The models span a range of biological scales and target a variety of datasets, such that like for like comparison between them is not always possible. I lay out a novel framework for facilitating comparison by defining some general abstract principles concerning the organization of cognition in the brain about which all of the models make a statement. The controversies that are revealed by scrutinizing the models within this framework highlight the fundamental questions that remain to be answered by future research. Ultimately, it is by combining these disparate accounts to build a unified model that bridges several levels of biological scale and accounts for multiple psychological phenomena that a full account of PRC function will be achieved.
我回顾了 Perirhinal 皮质（PRC）或邻近新皮质区域对认知贡献的七种模型。其中五个模型解决了识别记忆功能（Sohal 和 Hasselmo（2000）Network 11：169-190；Bogacz 等人（2001）J Comput Neurosci 10：5-23；Bogacz 和 Brown（2003a）Neurocomputing 52：1-6；Norman 和 O'Reilly（2003）Psychol Rev 110：611-646；Cowell 等人（2006）J Neurosci 26：12186-12197），两个模型解释了 PRC 在视觉辨别学习中的作用（Bussey 和 Saksida（2002）Eur J Neurosci 15：355-364；Cowell 等人（2010b）J Cogn Neurosci 22：2460-2479）。这些模型涵盖了一系列的生物学尺度，并针对各种数据集，因此它们之间的直接比较并不总是可行的。我提出了一个新的框架，通过定义一些关于大脑认知组织的一般抽象原则来促进比较，所有的模型都对这些原则进行了陈述。通过在这个框架内仔细研究模型，可以揭示出一些争议，这些争议突出了未来研究仍需回答的一些基本问题。最终，通过结合这些不同的解释来建立一个统一的模型，该模型跨越了几个生物学尺度，并解释了多个心理现象，才能实现对 PRC 功能的全面解释。
