手术及异维甲酸未能缓解进行性骨化性纤维发育不良患者的颌骨固定：两例报告
Failure of surgery and isotretinoin to relieve jaw immobilization in fibrodysplasia ossificans progressiva: report of two cases.
作者信息
Crofford L J, Brahim J S, Zasloff M A, Marini J C
机构信息
National Institutes of Health, Bethesda, MD 20892.
出版信息
J Oral Maxillofac Surg. 1990 Feb;48(2):204-8. doi: 10.1016/s0278-2391(10)80212-5.
Two patients with fibrodysplasia ossificans progressiva who presented with jaw immobilization due to formation of bone between the maxilla and mandible were treated with surgical resection of their ectopic bone in conjunction with experimental, adjunctive medical therapy using isotretinoin. Both patients had recurrence of their ectopic ossification within 2 months of surgery. Surgery to remove joint-bridging ossifications in FOP is not recommended.
两名进行性骨化性纤维发育不良患者因上颌骨和下颌骨之间形成骨组织而出现颌骨固定，接受了异位骨手术切除，并结合使用异维A酸进行实验性辅助药物治疗。两名患者均在手术后2个月内出现异位骨化复发。不建议对进行性骨化性纤维发育不良患者进行手术切除关节桥接骨化。
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