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妊娠血小板减少症的一种不常见表现。

An unusual presentation of gestational thrombocytopenia.

机构信息

Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Platelets. 2013;24(6):498-9. doi: 10.3109/09537104.2012.724484. Epub 2012 Sep 20.

Abstract

Thrombocytopenia is classically defined as a platelet count of less than 150 000/µl. Counts from 100 000 to 150 000/µl are considered mildly depressed, 50 000 to 100 000/µl moderately depressed, and less than 50 000/µl severely depressed. Thrombocytopenia occurs in about 10% of pregnant women. Gestational thrombocytopenia (GT) is a diagnosis of exclusion and considered the most prevalent cause of thrombocytopenia in pregnancy. GT accounts for almost 75% of cases of thrombocytopenia in pregnancy. The cause of GT is unclear, although existing studies denote the possibility of accelerated platelet consumption and the increased plasma volume during pregnancy. The presence of antiplatelet antibodies is not specific to GT. The degree of thrombocytopenia in GT is usually mild to moderate, usually remaining greater than 70 000/µl. Patients are asymptomatic with no evidence of bleeding and rarely preconception history of thrombocytopenia. The platelet count returns to normal within 2-12 weeks post partum. We wish to report a unique case of GT presenting as blurred vision due to retinal hemorrhages.

摘要

血小板减少症通常定义为血小板计数低于 150000/µl。计数在 100000 到 150000/µl 之间被认为是轻度降低,50000 到 100000/µl 为中度降低,小于 50000/µl 为重度降低。约 10%的孕妇会发生血小板减少症。妊娠性血小板减少症(GT)是一种排除性诊断,是妊娠中血小板减少症最常见的原因。GT 占妊娠中血小板减少症的近 75%。GT 的病因尚不清楚,尽管现有研究表明,妊娠期间血小板消耗加速和血浆容量增加的可能性。抗血小板抗体的存在并不能特异性提示 GT。GT 中的血小板减少症程度通常为轻度至中度,通常大于 70000/µl。患者无症状,无出血证据,且孕前很少有血小板减少症病史。血小板计数在产后 2-12 周内恢复正常。我们报告了一例 GT 的罕见病例,其表现为视网膜出血导致的视力模糊。

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