Suppr超能文献

[复发性宫颈癌术后大剂量腔内近距离放射治疗]

[High-dose intracavitary brachytherapy of a recurrent cervical cancer following surgery].

作者信息

Kumagaya H, Ito H, Hashimoto S

机构信息

Dept. of Radiology, Keio Univ., School of Med.

出版信息

Gan No Rinsho. 1990 Jan;36(1):51-6.

PMID:2299791
Abstract

Forty-nine postoperative cancer patients with a recurrent cervical cancer at the vaginal stump were treated with high-dose intracavitary brachytherapy with or without external irradiation. The intervals between their previous surgery and the vaginal recurrence ranged widely, from 4 months to 36 years. The overall 10-year survival rate after radiotherapy was 48%. The patients were classified into two groups, according to the tumor size that was evaluated by rectovaginal examination at time of recurrence, that is, one group without a palpable mass at the vaginal stump and one with a palpable mass. The 10 year-survival rate with or without the palpable mass was 8% and 80%, respectively. External irradiation combined with brachytherapy could not modify the survival rate of those that had been treated by brachytherapy alone in the group without the palpable mass. On the other hand, the incidence of late intestinal complications was increased by the combination of external irradiation. This result suggests that the most important prognostic factor in cases of a recurrent cervical cancer at the stump is the tumor size.

摘要

49例阴道残端复发性宫颈癌的术后癌症患者接受了高剂量腔内近距离放射治疗,部分患者联合外照射。她们上次手术至阴道复发的间隔时间差异很大,从4个月到36年不等。放疗后的总体10年生存率为48%。根据复发时经直肠阴道检查评估的肿瘤大小,将患者分为两组,即阴道残端无可触及肿块的一组和有可触及肿块的一组。有或无可触及肿块患者的10年生存率分别为8%和80%。对于阴道残端无可触及肿块的组,外照射联合近距离放射治疗并不能改变单纯接受近距离放射治疗患者的生存率。另一方面,外照射联合治疗会增加晚期肠道并发症的发生率。这一结果表明,残端复发性宫颈癌病例中最重要的预后因素是肿瘤大小。

相似文献

2
Radiotherapy for centrally recurrent cervical cancer of the vaginal stump following hysterectomy.
Gynecol Oncol. 1997 Nov;67(2):154-61. doi: 10.1006/gyno.1997.4855.
3
High dose-rate intracavitary brachytherapy for cervical carcinomas with lower vaginal infiltration.
Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1157-66. doi: 10.1016/j.ijrobp.2007.02.014. Epub 2007 Apr 24.
6
Transperineal high-dose-rate interstitial radiation therapy in the management of gynecologic malignancies.
Strahlenther Onkol. 2003 Nov;179(11):737-41. doi: 10.1007/s00066-003-1069-1.
7
High dose rate intracavitary brachytherapy for recurrent cervical cancer of the vaginal stump following hysterectomy.
Int J Radiat Oncol Biol Phys. 1991 May;20(5):927-32. doi: 10.1016/0360-3016(91)90187-9.
9
Radiation therapy of pelvic recurrence after radical hysterectomy for cervical carcinoma.
Gynecol Oncol. 1998 Aug;70(2):241-6. doi: 10.1006/gyno.1998.5093.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验