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全髋关节置换术后预防手术部位感染的最相关策略:指南建议和专家意见。

Most relevant strategies for preventing surgical site infection after total hip arthroplasty: guideline recommendations and expert opinion.

机构信息

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.

出版信息

Am J Infect Control. 2013 Mar;41(3):221-6. doi: 10.1016/j.ajic.2012.03.027. Epub 2012 Sep 21.

Abstract

BACKGROUND

Numerous strategies are available to prevent surgical site infections in hip arthroplasty, but there is no consensus on which might be the best. This study examined infection prevention strategies currently recommended for patients undergoing hip arthroplasty.

METHODS

Four clinical guidelines on infection prevention/orthopedics were reviewed. Infection control practitioners, infectious disease physicians, and orthopedic surgeons were consulted through structured interviews and an online survey. Strategies were classified as "highly important" if they were recommended by at least one guideline and ranked as significantly or critically important by ≥75% of the experts.

RESULTS

The guideline review yielded 28 infection prevention measures, with 7 identified by experts as being highly important in this context: antibiotic prophylaxis, antiseptic skin preparation of patients, hand/forearm antisepsis by surgical staff, sterile gowns/surgical attire, ultraclean/laminar air operating theatres, antibiotic-impregnated cement, and surveillance. Controversial measures included antibiotic-impregnated cement and, considering recent literature, laminar air operating theatres.

CONCLUSIONS

Some of these measures may already be accepted as routine clinical practice, whereas others are controversial. Whether these practices should be continued for this patient group will be informed by modeling the cost-effectiveness of infection prevention strategies. This will allow predictions of long-term health and cost outcomes and thus inform decisions on how to best use scarce health care resources for infection control.

摘要

背景

有许多策略可用于预防髋关节置换术的手术部位感染,但哪种策略可能是最好的还没有共识。本研究检查了目前推荐给髋关节置换术患者的感染预防策略。

方法

对 4 篇关于感染预防/骨科的临床指南进行了回顾。通过结构化访谈和在线调查,咨询了感染控制从业者、传染病医生和骨科医生。如果至少有一种指南推荐了某项策略,并且≥75%的专家认为其非常重要或至关重要,则将其归类为“高度重要”。

结果

指南审查产生了 28 项感染预防措施,其中有 7 项被专家确定为在这种情况下高度重要:抗生素预防、患者的皮肤消毒准备、手术人员的手部/前臂消毒、无菌手术服/手术服、超净/层流手术室、抗生素浸渍水泥和监测。有争议的措施包括抗生素浸渍水泥,考虑到最近的文献,还有层流手术室。

结论

其中一些措施可能已经被接受为常规临床实践,而其他措施则存在争议。对于这群患者,这些做法是否应该继续,将通过对感染预防策略的成本效益进行建模来告知。这将允许预测长期的健康和成本结果,从而为如何最好地利用稀缺的医疗保健资源来控制感染做出决策。

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