Sexual Health Program, Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA 02215, USA.
J Clin Oncol. 2012 Oct 20;30(30):3712-9. doi: 10.1200/JCO.2012.41.7915. Epub 2012 Sep 24.
Sexual dysfunction is one of the most common and distressing consequences of cancer treatment. Although some treatment-related sexual adverse effects are short-term, many survivors face long-term effects such as treatment-induced menopause, altered gonadal function, and significant surgical disfigurement. Profound sexual dysfunction has been shown to have a significant negative effect on quality of life. Although these problems have been well documented and there are a range of intervention strategies that can help patients cope with treatment-related sexual problems, many survivors do not feel prepared for potential sexual changes and often do not receive adequate support to manage sexual dysfunction. Numerous barriers contribute to this underprovided aspect of survivorship care, including lack of provider training and access to readily available resources. In addition, psychological, relational, and cultural factors significantly influence sexuality but are often not taken into consideration in research and clinical practice. By taking an integrative approach and providing survivors with appropriate screening, information, and support, sexual dysfunction and accompanying distress can be significantly alleviated. In this article, we aim to provide a concise review of the most common sexual problems experienced by survivors and highlight some of the most promising evidence-based practices for assessment and intervention. We also address limitations encountered in research and practice and explore future directions, including suggestions for adopting an integrative treatment model to address sexual dysfunction in a cancer survivorship treatment setting.
性功能障碍是癌症治疗最常见和最令人痛苦的后果之一。尽管一些与治疗相关的性功能不良影响是短期的,但许多幸存者面临长期影响,如治疗引起的更年期、性腺功能改变和明显的手术毁容。严重的性功能障碍已被证明对生活质量有重大负面影响。尽管这些问题已经得到很好的记录,并且有一系列干预策略可以帮助患者应对与治疗相关的性问题,但许多幸存者对潜在的性变化没有做好准备,并且经常得不到足够的支持来管理性功能障碍。许多障碍导致了生存护理中这一未得到充分提供的方面,包括缺乏提供者培训和获得现成资源的机会。此外,心理、关系和文化因素对性行为有重大影响,但在研究和临床实践中往往没有考虑到这些因素。通过采取综合方法,为幸存者提供适当的筛查、信息和支持,可以显著减轻性功能障碍和伴随的痛苦。在本文中,我们旨在对幸存者最常见的性问题进行简明扼要的综述,并强调一些最有前途的基于证据的评估和干预实践。我们还讨论了研究和实践中遇到的局限性,并探讨了未来的方向,包括提出采用综合治疗模式来解决癌症生存者治疗环境中的性功能障碍的建议。