西地那非（伟哥）与心脏
Sildenafil (viagra) and the heart.
作者信息
Chamsi-Pasha H
机构信息
King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.
出版信息
J Family Community Med. 2001 May;8(2):63-6.
Sildenafil (Viagra) is the most effective oral therapy currently available for erectile dysfunction. Patients should be given clear instructions regarding the use of sildenafil. The most common side effects include flushing, headaches, dyspepsia, and transient visual changes. In combination with nitrates, it can and has caused fatal hypotension. It should not be prescribed to patients on nitrates. Additionally, nitrates should not be administered to anyone who has recently ingested sildenafil. Synergetic blood pressure lowering has not been observed when sildenafil was used with other classes of antihypertensives. Sildenafil is not offered to patients with low cardiac output states, those on intensive regimens to prevent heart failure or those with acute coronary ischemia.
西地那非（万艾可）是目前治疗勃起功能障碍最有效的口服药物。应向患者清楚说明西地那非的使用方法。最常见的副作用包括潮红、头痛、消化不良和短暂的视觉变化。与硝酸盐类药物合用会且已导致致命性低血压。禁止给正在服用硝酸盐类药物的患者开具此药。此外，近期服用过西地那非的患者也不应使用硝酸盐类药物。西地那非与其他种类的抗高血压药物合用时未观察到协同性血压降低的情况。低心排血量状态的患者、正在接受强化治疗以预防心力衰竭的患者或患有急性冠状动脉缺血的患者不应使用西地那非。
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