Ma Xian-Liang, Zhang Yi
Department of Vector Control, National Institute for Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Pathogenic Parasites and Vector Biology, Min-. istry of Health, Shanghai 200025, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2012 Jun;24(3):350-2, 357.
Peroxiredoxin (Prx) belongs to a peroxidase family of antioxidant enzymes distributed ubiquitously in aerobic organisms such as yeast, fungi, parasites, mammals and humans. It plays an important role in the defense of reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by aerobic organisms. This article introduces the classification, mechanism of Prx and the progress of research on Prx in invertebrates.
过氧化物酶(Prx)属于抗氧化酶的过氧化物酶家族,广泛分布于需氧生物中,如酵母、真菌、寄生虫、哺乳动物和人类。它在防御需氧生物产生的活性氧(ROS)和活性氮(RNS)方面发挥着重要作用。本文介绍了Prx的分类、作用机制以及在无脊椎动物中对Prx的研究进展。