Chung Cho-Yun, Park Sang-Woo, Myung Eun, Cho Dong-Keun, Song Young A, Park Kang-Jin, Jang Hee-Chang, Joo Young-Eun
Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Korean J Gastroenterol. 2012 Sep 25;60(3):166-71. doi: 10.4166/kjg.2012.60.3.166.
Kaposi sarcoma (KS) is a vascular neoplasm, which is fairly prevalent in acquired immunodeficiency syndrome (AIDS) patients. Mucocutaneous and lymph node involvements are characteristic features of KS in AIDS patients. The involvement of gastrointestinal tract occurs in 40% of KS patients and leads to significant morbidity and mortality. In the highly active antiretroviral therapy (HAART) era, the rate of AIDS related KS has fallen with control of human immunodeficiency virus (HIV) viremia. However, it is still recognized as the primary AIDS-defining illness, and the proportion of AIDS diagnoses made due to KS ranged from 4.1% to 7.5%. In Korea, AIDS-related KS has been report in low rate incidence. Its gastrointestinal involvements are rarely reported. To date, five cases have been recorded in Korea. Herein, we present an additional case of gastrointestinal KS as the AIDS-defining illness and review of the Korean medical literature.
卡波西肉瘤（KS）是一种血管性肿瘤，在获得性免疫缺陷综合征（AIDS）患者中相当常见。皮肤黏膜和淋巴结受累是艾滋病患者卡波西肉瘤的特征性表现。胃肠道受累见于40%的卡波西肉瘤患者，可导致显著的发病率和死亡率。在高效抗逆转录病毒治疗（HAART）时代，随着人类免疫缺陷病毒（HIV）病毒血症得到控制，与艾滋病相关的卡波西肉瘤发病率有所下降。然而，它仍被视为主要的艾滋病定义疾病，因卡波西肉瘤导致的艾滋病诊断比例在4.1%至7.5%之间。在韩国，艾滋病相关卡波西肉瘤的发病率较低。其胃肠道受累情况鲜有报道。迄今为止，韩国已记录了5例。在此，我们报告1例作为艾滋病定义疾病的胃肠道卡波西肉瘤病例，并对韩国医学文献进行综述。
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