Service d'ORL et de chirurgie cervico-faciale, pôle neuroscience tête et cou, hôpital Gui de Chauliac, CHU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Dec;129(6):308-14. doi: 10.1016/j.anorl.2012.03.006. Epub 2012 Sep 27.
Review of the treatment of cervical paraganglioma.
Review of the literature based on a Medline database.
The treatment of choice consists of a multidisciplinary approach based on a detailed clinical, laboratory and radiological work-up. Vascular reconstruction may be necessary when the tumour invades the artery wall. The main complication of surgery is damage to cranial nerves involved in speech and/or swallowing. Treatment of bilateral tumours must be conducted in two stages. The first side to be operated depends on the sites and size of the tumours, as the primary objective is to avoid bilateral vagus nerve palsy. Radiotherapy has been used to treat paragangliomas for several years and achieves tumour stabilization in the majority of cases. Potential indications reported in the literature are: inoperable tumours, recurrence after surgery, some bilateral tumours and malignant tumours.
Surgery is the standard treatment for cervical paraganglioma. Radiotherapy can be proposed when surgery is contraindicated.
回顾颈部副神经节瘤的治疗方法。
基于 Medline 数据库进行文献回顾。
治疗方法选择以详细的临床、实验室和影像学检查为基础的多学科治疗方法。当肿瘤侵犯动脉壁时，可能需要进行血管重建。手术的主要并发症是损伤参与言语和/或吞咽的颅神经。双侧肿瘤的治疗必须分两阶段进行。手术的第一侧取决于肿瘤的部位和大小，因为主要目标是避免双侧迷走神经麻痹。多年来，放射治疗一直被用于治疗副神经节瘤，大多数情况下可使肿瘤稳定。文献中报道的潜在适应证包括：无法手术的肿瘤、手术后复发、一些双侧肿瘤和恶性肿瘤。
手术是颈部副神经节瘤的标准治疗方法。当手术禁忌时，可以提出放射治疗。
Zotero 插件