Novick A C, Jackson C L, Straffon R A
Department of Urology, Cleveland Clinic Foundation, Ohio 44195.
J Urol. 1990 Mar;143(3):452-7. doi: 10.1016/s0022-5347(17)39988-3.
From 1972 to 1988, 108 patients underwent renal autotransplantation for renal artery disease (67), ureteral replacement (27), or renal cell carcinoma present bilaterally or in a solitary kidney (14). The most common indication for renal autotransplantation was to allow extracorporeal repair of complex branch renal artery lesions. Of the 54 patients in this group technically satisfactory branch renal arterial reconstruction and a successful clinical outcome were achieved in 52 (96%). Renal autotransplantation is the treatment of choice in these patients and also in selected children with main renal artery disease. Renal autotransplantation provided excellent results in 25 of 27 patients (92%) who required replacement of all or a major portion of the ureter. Over-all renal function was well preserved in these patients and only 1 has experienced chronic bacteriuria. Renal autotransplantation is a useful alternative to ileal interposition in this setting. Extracorporeal partial nephrectomy and renal autotransplantation were successful in 12 of 14 patients (85%) undergoing a nephron-sparing operation for renal cell carcinoma. In situ techniques are associated with less morbidity and currently are preferred in this group.
1972年至1988年期间,108例患者因肾动脉疾病(67例)、输尿管置换(27例)或双侧或孤立肾存在肾细胞癌(14例)接受了自体肾移植。自体肾移植最常见的适应证是允许对复杂的肾动脉分支病变进行体外修复。在该组54例患者中,52例(96%)实现了技术上满意的肾动脉分支重建和成功的临床结果。自体肾移植是这些患者以及部分患有主肾动脉疾病儿童的首选治疗方法。在27例需要置换全部或大部分输尿管的患者中,25例(92%)通过自体肾移植取得了优异的效果。这些患者的总体肾功能得到了良好的保留,只有1例出现慢性菌尿。在这种情况下,自体肾移植是回肠代输尿管术的一种有用替代方法。14例因肾细胞癌接受保留肾单位手术的患者中,12例(85%)通过体外部分肾切除术和自体肾移植获得成功。原位技术的发病率较低,目前在该组中更受青睐。