Kotani N, Sakai T, Ohshima S, Kudoh A, Dobashi N, Matsuki A
Department of Anesthesiology, University of Hirosaki School of Medicine.
Masui. 1990 Jan;39(1):114-7.
We reported a 54-year-old male with essential thrombocythemia, who underwent coronary artery bypass grafting. Anesthesia was maintained with enflurane in nitrous oxide and oxygen supplemented with fentanyl. Heparin 7mg. kg-1 was administered intravenously to obtain adequate anticoagulant effect during 89 minutes of extracorporeal circulation. Aspirin and dipyridamole were also administered as anti-platelet therapy. No complications were observed during and after anesthesia. It is advocated that administration of anticoagulants such as heparin, aspirin and dipyridamole is effective to prevent thrombus formation.
我们报告了一名54岁患有原发性血小板增多症的男性患者，该患者接受了冠状动脉搭桥术。麻醉维持采用安氟醚，吸入氧化亚氮和氧气，并补充芬太尼。静脉注射肝素7mg/kg，以在89分钟的体外循环期间获得足够的抗凝效果。还给予阿司匹林和双嘧达莫作为抗血小板治疗。麻醉期间及术后未观察到并发症。有人主张使用肝素、阿司匹林和双嘧达莫等抗凝剂对预防血栓形成有效。
