线粒体混合的问题。
The problem with mixing mitochondria.
机构信息
Department of Genetics, Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK.
出版信息
Cell. 2012 Oct 12;151(2):246-8. doi: 10.1016/j.cell.2012.09.028.
PMID:23063117
Abstract
Mixing of mitochondrial DNAs (heteroplasmy) is unfavorable for reasons unknown. Sharpley et al. show that heteroplasmy has surprising genetic and behavioral effects in mice, even when each haplotype alone produces a normal phenotype. This interference is bioenergetic and may have contributed to the evolution of sexes.
摘要
线粒体 DNA 的混合（异质性）是不利的，原因尚不清楚。Sharpley 等人表明，异质性在小鼠中具有惊人的遗传和行为效应，即使每种单倍型单独产生正常表型也是如此。这种干扰是生物能量的，可能促成了性别的进化。
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