Department of Cardiology, Aviation General Hospital, An Ding Men Wai Bei Yuan Road 3, Beijing, 100012, China.
Cell Biochem Biophys. 2013 Apr;65(3):485-9. doi: 10.1007/s12013-012-9438-y.
The objective of the study was to explore the prevalence and characteristics of myocardial bridging in patients who underwent coronary angiography and to also evaluate the correlation between bridged coronary segments and atherosclerosis. For this purpose, clinical materials of 1,500 patients who had received coronary angiography were retrospectively analyzed. The location and length of the myocardial bridge were recorded as well as the extent and location of coronary artery stenosis was described. Segments proximal and distal to the bridging were evaluated for coronary arteriosclerosis as were the remaining coronary segments. We found that myocardial bridging was present in 179 (11.9 %) patients. Bridges were frequently (84.9 %) localized in the mid-distal segment of the left anterior descending (LAD) artery. Myocardial bridging was not considered a significant risk factor for coronary atherosclerosis (odds ratio 0.58) compared with traditional cardiovascular risk factors. The incidence of coronary arteriosclerosis in the distal segments was significantly less affected than the proximal segments (P < 0.01). It was, therefore, concluded that myocardial bridging frequently localized in the mid-distal segment of the LAD artery. The presence of myocardial bridging promotes proximal atherosclerosis but it is not an additional risk factor for coronary atherosclerosis.
本研究旨在探讨行冠状动脉造影术患者心肌桥的发生率及特点,并评估桥血管段与动脉粥样硬化之间的相关性。为此,我们回顾性分析了 1500 例行冠状动脉造影术患者的临床资料。记录心肌桥的位置和长度,描述冠状动脉狭窄的程度和位置。评估桥血管段近段和远段以及剩余冠状动脉段的动脉粥样硬化情况。结果发现,179 例(11.9%)患者存在心肌桥。桥血管多位于左前降支(LAD)的中远端(84.9%)。与传统心血管危险因素相比,心肌桥不是冠状动脉粥样硬化的显著危险因素(比值比 0.58)。与近段相比,远段的动脉粥样硬化发生率明显较低(P < 0.01)。因此,结论为心肌桥常位于 LAD 的中远端。心肌桥的存在可促进近端动脉粥样硬化,但不是冠状动脉粥样硬化的额外危险因素。