[乳腺癌的预后因素]

[Prognostic factors in breast cancer].

作者信息

Georgescu R, Coroş M F, Stolnicu Simona, Podeanu Daniela, Sorlea S, Roşca Anca, Copotoiu C

机构信息

Universitatea de Medicină si Farmacie Târgu Mureş.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2012 Jan-Mar;116(1):262-7.

PMID:23077906

Abstract

UNLABELLED

Survival in breast cancer is determined by many factors, their influence is different. The aim of the study is to assess the impact on survival of various prognostic factors.

MATERIAL AND METHODS

We studied a total of 198 cases of histologically confirmed breast cancer patients, and we evaluated the impact of prognostic factors on survival.

RESULTS

The most important factor influencing survival is the preset of axillary metastasis(p: 0.0001). Other important prognostic factors are: tumor size (p: 0.003), tumor grading (p: 0.0025), N stage (p: 0.0001.) lymphovascular invasion (p 0.0005) and Nottingham Prognostic Index (p: 0.0109). The factors with no impact on survival were: histological type (p: 0.82), number of lymph nodes affected(p: 0.23), tumor necrosis(p: 0.49) and inflammatory infiltration (p: 0.2).

CONCLUSIONS

The most important prognostic factors are: axillary metastasis followed by tumor grading, NPI and lymphovascular invasion.

摘要

未标注

乳腺癌的生存率由多种因素决定，它们的影响各不相同。本研究的目的是评估各种预后因素对生存率的影响。

材料与方法

我们共研究了198例经组织学确诊的乳腺癌患者，并评估了预后因素对生存率的影响。

结果

影响生存率的最重要因素是腋窝转移的存在（p：0.0001）。其他重要的预后因素包括：肿瘤大小（p：0.003）、肿瘤分级（p：0.0025）、N分期（p：0.0001）、淋巴管浸润（p：0.0005）和诺丁汉预后指数（p：0.0109）。对生存率无影响的因素有：组织学类型（p：0.82）、受累淋巴结数量（p：0.23）、肿瘤坏死（p：0.49）和炎症浸润（p：0.2）。