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[楚科奇海沿岸和大陆地区原住民接触多氯联苯(PCBs)的特点]

[Peculiarities of exposure to polychlorinated biphenyls (PCBS) in the indigenous population of the coastal and mainland Chukotka].

作者信息

Dudarev A A, Chupakhin V S, Ivanova Z S, Lebedev G B

出版信息

Gig Sanit. 2012 Jul-Aug(4):22-8.

Abstract

The indigenous people of coastal areas show a low percentage of low chlorinated and dioxin-like PCB congeners (as opposed to mainland aborigines) with a significant proportion of the "triad" in the amount of PCBs. 5 years after the first survey the ratio of the analyzed groups of PCB congeners in the blood of parturients - mothers, as well as in the fetus - child in the coastal Chukotka remained unchanged, indicating that the equal share rate of clearance-accumulation of congeners and is almost equal share content of PCB congeners in the mother and child. The average duration of half-lives of PCB congeners (#105-187) from the mother's body was 4-6 years (for the sum of PCBs - 5.7 years), which is broadly consistent with the results of foreign studies. The composition of PCB congeners in the blood of the continental population significantly differs from those in the food, while coastal residents--similar to the composition of PCBs in marine mammals. The content of PCB congeners in the domestic sources of pollution has no resemblance to the composition of PCBs in the blood of the natives.

摘要

沿海地区的原住民体内低氯和二恶英类多氯联苯同系物的比例较低(与大陆原住民相反),多氯联苯含量中“三联体”的比例较高。首次调查5年后,楚科奇沿海地区产妇(母亲)以及胎儿(孩子)血液中分析的多氯联苯同系物组的比例保持不变,这表明同系物的清除-积累份额相等,且母亲和孩子体内多氯联苯同系物的含量份额几乎相等。多氯联苯同系物(#105 - 187)从母亲体内排出的平均半衰期为4 - 6年(多氯联苯总量为5.7年),这与国外研究结果大致一致。大陆人口血液中的多氯联苯同系物组成与食物中的显著不同,而沿海居民血液中的多氯联苯组成与海洋哺乳动物中的相似。家庭污染源中多氯联苯同系物的含量与当地居民血液中多氯联苯的组成毫无相似之处。

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