Kasahara Hirofumi, Shimizu Hideyuki, Yozu Ryohei
Department of Cardiovascular Surgery, National Hospital Organization Saitama Hospital, Wako, Japan.
Ann Vasc Surg. 2013 Apr;27(3):291-8. doi: 10.1016/j.avsg.2012.04.024. Epub 2012 Oct 18.
We report our 11-year experience of juxtarenal aortic aneurysm (JAA) repair with suprarenal aortic cross-clamping.
We retrospectively reviewed 51 consecutive JAA repairs performed between 2000 and 2010. In all 51 patients, aneurysms were replaced by prosthetic grafts with simple suprarenal aortic cross-clamping. No special renal protective measures (except inter-renal cross-clamping) were performed during interruption of perfusion to kidneys. For inter-renal cross-clamping, the aortic cross-clamp was placed from below one renal artery to above the other renal artery to maintain hemilateral renal perfusion. This technique was applied in 27 patients (54%). Postoperative complications, renal function, and survival were evaluated.
There were no deaths. The average renal ischemia time was 28.9 ± 9.7 minutes. Postoperatively, transient renal failure (defined as an estimated glomerular filtration rate of <30 mL/min/1.73 m(2)) occurred in 14% of the patients. The postoperative decrease of estimated glomerular filtration rate compared with the preoperative value was significantly smaller in the inter-renal clamp group (7.4% ± 16%) than in the suprarenal clamp group (17.5% ± 16%) (P < 0.05, unpaired t test). However, renal dysfunction was temporary and recovered to baseline before discharge with conservative therapy in all patients except one. In addition, renal function was generally preserved at 1 year after surgery.
Surgical repair of JAA can be performed with simple cross-clamping and an acceptable renal ischemic time, achieving excellent results. Inter-renal cross-clamping reduces renal damage compared with suprarenal cross-clamping.
我们报告了采用肾上主动脉交叉钳夹术治疗近肾主动脉瘤(JAA)11年的经验。
我们回顾性分析了2000年至2010年间连续进行的51例JAA修复术。在所有51例患者中,采用单纯肾上主动脉交叉钳夹术用人工血管置换动脉瘤。在肾脏灌注中断期间未采取特殊的肾脏保护措施(除肾间交叉钳夹外)。对于肾间交叉钳夹,将主动脉交叉钳置于一侧肾动脉下方至另一侧肾动脉上方,以维持单侧肾脏灌注。该技术应用于27例患者(54%)。评估术后并发症、肾功能和生存率。
无死亡病例。平均肾脏缺血时间为28.9±9.7分钟。术后,14%的患者出现短暂性肾衰竭(定义为估计肾小球滤过率<30 mL/min/1.73 m²)。与术前值相比,肾间钳夹组术后估计肾小球滤过率的下降幅度(7.4%±16%)明显小于肾上钳夹组(17.5%±16%)(P<0.05,非配对t检验)。然而,除1例患者外,所有患者的肾功能障碍均为暂时性,经保守治疗后在出院前恢复至基线水平。此外,术后1年时肾功能总体得以保留。
JAA的手术修复可通过简单的交叉钳夹术及可接受的肾脏缺血时间来完成,取得良好效果。与肾上交叉钳夹相比,肾间交叉钳夹可减少肾脏损伤。