Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510 México DF, Mexico.
J Steroid Biochem Mol Biol. 2013 Mar;134:45-50. doi: 10.1016/j.jsbmb.2012.10.007. Epub 2012 Oct 17.
The naturally occurring dinorcholanic lactone vespertilin and two other non-natural derivatives bearing the 5α-hydroxy-6-oxo moiety were synthesized starting from the readily available steroid sapogenin diosgenin. The obtained compounds showed plant growth promoting activity in the bean's second internode elongation assay.
从易得甾体皂素薯蓣皂甙元出发,合成了天然的胆甾烷内酯蝙蝠葛苏林和另外两个带有 5α-羟基-6-氧代部分的非天然衍生物。所得到的化合物在豆类的第二节间伸长测定中显示出植物生长促进活性。