芳环的 18F 标记。
18F labeling of arenes.
机构信息
Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
出版信息
Angew Chem Int Ed Engl. 2012 Nov 12;51(46):11426-37. doi: 10.1002/anie.201204687. Epub 2012 Oct 19.
PMID:23086547
Abstract
Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists to enter the field of (18) F-radiochemistry and provide generic solutions to address the well-recognized challenges of late-stage fluorination. This Minireview focuses on recent developments in the (18)F-labeling of aromatic substrates.
摘要
分子成像是一个蓬勃发展的领域，其中正电子发射断层扫描（PET）技术处于领先地位。这种趋势促使众多合成化学家进入（18）F-放射性化学领域，并提供通用解决方案来应对后期氟代反应所面临的公认挑战。本文综述了芳香底物的（18）F 标记的最新进展。
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