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口腔癌患者椎间孔内种植体的放置:在消融手术期间还是延迟?一项 5 年回顾性研究。

Interforaminal implant placement in oral cancer patients: during ablative surgery or delayed? A 5-year retrospective study.

机构信息

Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

出版信息

Int J Oral Maxillofac Surg. 2013 May;42(5):651-5. doi: 10.1016/j.ijom.2012.09.013. Epub 2012 Oct 24.

Abstract

In a retrospective study, two mandibular prosthetic rehabilitation strategies supported by implants in oral cancer patients were evaluated: implants placed in the non-resected edentulous symphyseal area during ablative surgery (DAS implants); or at a later stage (postponed (P) implants). Medical files of patients from two head-neck oncology groups from 2000 to 2005 were screened for study inclusion. DAS protocol was used in one group and P protocol in the other. After a 5 year follow-up of 261 edentulous patients with oral cancer in the second group, P implants were placed in 27 patients to support an overdenture. Of the 249 edentulous patients in the first group, 82 patients were given an implant supported overdenture using the DAS implant protocol. Regarding implant loss, no statistically significant differences were seen between the DAS and P implants. In the DAS group, more patients benefited from an implant-supported lower overdenture (39 versus 11%, respectively), and they received their overdenture on average 20.0 months sooner (sd=11.01, p<0.001) after ablative surgery. 17.1% of DAS implants and 4.6% of P implants were never loaded due to tumour and patient related factors including unfavourable implant soft tissue, tumour recurrence near the implant, or radiotherapy induced trismus.

摘要

在一项回顾性研究中,评估了两种在下颌骨肿瘤患者中使用种植体支持的下颌义齿修复策略:在根治性手术中于未切除的牙槽骨颏部区域植入种植体(DAS 种植体);或在后期(延期 P 种植体)植入。筛选了 2000 年至 2005 年来自两个头颈肿瘤学组的患者的医疗档案以纳入研究。一组采用 DAS 方案,另一组采用 P 方案。在对第二组 261 名接受口腔癌根治性手术的无牙颌患者进行 5 年随访后,有 27 名患者放置 P 种植体以支持覆盖义齿。在第一组的 249 名无牙颌患者中,82 名患者使用 DAS 种植体方案接受了种植体支持的覆盖义齿。关于种植体失败,DAS 和 P 种植体之间没有统计学差异。在 DAS 组中,更多患者受益于种植体支持的下颌覆盖义齿(分别为 39%和 11%),他们在根治性手术后平均提前 20.0 个月(sd=11.01,p<0.001)获得覆盖义齿。由于肿瘤和患者相关因素,包括种植体软组织不理想、种植体附近肿瘤复发或放疗引起的张口受限,DAS 种植体的 17.1%和 P 种植体的 4.6%从未负载。

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