一种用于亮氨酸拉链标记蛋白的模块化非共价转导系统。
A modular and noncovalent transduction system for leucine-zipper-tagged proteins.
机构信息
Radboud University Nijmegen, Institute for Molecules and Materials, Department of Organic Chemistry, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
出版信息
Chembiochem. 2011 Oct 17;12(15):2294-7. doi: 10.1002/cbic.201100481.
Modes of transport: A leucine-zipper-tagged GFP was transported into cells by "zipping" it (red) to it's complementary leucine zipper (blue) functionalized with a cell-penetrating peptide (CPP). This transport system has an inherent modularity as the CPP is "clicked" to the leucine zipper, and then noncovalently bound to the protein, thus making it system particularly useful for targeting studies.
运输方式
通过“拉链”（红色）将带有亮氨酸拉链标签的 GFP 与带有细胞穿透肽（CPP）的互补亮氨酸拉链（蓝色）“拉链”在一起，将其运送到细胞中。这种运输系统具有固有模块化性，因为 CPP 被“点击”到亮氨酸拉链上，然后与蛋白质非共价结合，从而使其成为特别有用的靶向研究系统。
Zotero 插件