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结节病病程中的高钙血症和肾衰竭——病例报告

Hypercalcemia and renal failure in the course of sarcoidosis--case report.

作者信息

Kempisty Anna, Kuś Jan

机构信息

Hiperkalcemia i uszkodzenie nerek w przebiegu sarkoidozy--opis przypadku.

出版信息

Pneumonol Alergol Pol. 2012;80(6):570-5.

Abstract

Disturbances of calcium metabolism such as hypercalcemia or/and hypercalciuria in the course of sarcoidosis can be a cause of renal failure in some patients. Life threatening hypercalcemia in sarcoidosis patients is not very frequent. Severe hypercalcemia leading to renal insufficiency is a very rare condition. We present a case of 53-year old man who was admitted to Department of Lung Diseases because of hypercalcemic syndrome and renal failure, and in whom diagnosis of sarcoidosis was made. He was successfully treated with systemic corticosteroids. In this article we present physiological mechanism of hypercalcemia in sarcoidosis patients, mechanism of renal damage and management of these difficult problems.

摘要

结节病过程中钙代谢紊乱,如高钙血症或/和高钙尿症,可能是部分患者肾衰竭的病因。结节病患者出现危及生命的高钙血症并不常见。导致肾功能不全的严重高钙血症是一种非常罕见的情况。我们报告一例53岁男性患者,因高钙血症综合征和肾衰竭入住肺病科,最终确诊为结节病。他接受全身糖皮质激素治疗后获得成功。本文阐述了结节病患者高钙血症的生理机制、肾损伤机制以及这些难题的处理方法。

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