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急性会厌炎:科威特47例患者的回顾性研究

Acute epiglottitis: a retrospective review of 47 patients in Kuwait.

作者信息

Qazi Imtiaz Majid, Jafar Abdul Mohsin, Hadi Khalid Al Abdul, Hussain Zakir

机构信息

Department of ENT, Zain and Al Sabah Hospitals, P O Box 4078, Safat, Kuwait, 13041 Kuwait.

出版信息

Indian J Otolaryngol Head Neck Surg. 2009 Dec;61(4):301-5. doi: 10.1007/s12070-009-0087-4. Epub 2010 Jan 9.

Abstract

OBJECTIVES

Acute epiglottitis is a potentially life threatening condition which can lead to fatal airway obstruction in previously healthy individuals. The present study was undertaken to assess the clinical features, management and patient outcomes of epiglottitis in Kuwait over an eight year period.

DESIGN

Case series.

SETTING

Al Sabah Hospital, Kuwait.

METHODS

All patients admitted to the ENT department of Al Sabah hospital between January 2000 and January 2008 with the diagnosis of acute epiglottitis were included in this retrospective study. The diagnosis of acute epiglottitis was established by visualization of inflamed epiglottis either on indirect laryngoscopy or flexible fibreoptic/direct laryngoscopy.

RESULTS

47 cases were identified, 5 children and 42 adults. There were 32 males and 15 females, in the age range of 5 to 66 years. Peak incidence was in the third decade. 31 patients had co-morbid conditions, 18 patients (38.2%) had diabetes, 8 patients (17%) had hypertension and 3 patients (6.3%) had dental caries. Majority of the patients (89.3%) presented with sore throat as their chief complaint. All patients were febrile on presentation. The classical "thumb sign" on lateral neck radiograph was seen in 32 patients (68%). Blood cultures were collected from 22 patients (46.8%), all were negative. Ceftriaxone was the commonest empirical antibiotic prescribed. 7 patients required airway intervention (5 with endotracheal intubation and 2 with tracheostomy). There were no deaths in our study.

CONCLUSION

In Kuwait, acute epiglottis is commoner in adults than in children. It is imperative to secure the airway and to start the patients on broad spectrum antibiotics and steroids as early as possible. In general, the prognosis is good with antimicrobial therapy, close monitoring and selective airway intervention, in the form of intubation / tracheostomy, for patients with stridor or shortness of breath.

摘要

目的

急性会厌炎是一种可能危及生命的疾病,可导致既往健康个体出现致命的气道梗阻。本研究旨在评估科威特8年间会厌炎的临床特征、治疗及患者预后。

设计

病例系列研究。

地点

科威特萨巴赫医院。

方法

本回顾性研究纳入了2000年1月至2008年1月期间在萨巴赫医院耳鼻喉科确诊为急性会厌炎的所有患者。急性会厌炎的诊断通过间接喉镜检查或纤维软镜/直接喉镜检查发现会厌发炎来确定。

结果

共确诊47例,其中儿童5例,成人42例。男32例,女15例,年龄在5至66岁之间。发病高峰在第三个十年。31例患者有合并症,18例(38.2%)患有糖尿病,8例(17%)患有高血压,3例(6.3%)患有龋齿。大多数患者(89.3%)以咽痛为主要主诉就诊。所有患者就诊时均发热。32例患者(68%)的颈部侧位X线片可见典型的“拇指征”。22例患者(46.8%)进行了血培养,结果均为阴性。头孢曲松是最常用的经验性抗生素。7例患者需要气道干预(5例行气管插管,2例行气管切开术)。本研究中无死亡病例。

结论

在科威特,急性会厌炎在成人中比在儿童中更常见。必须确保气道安全,并尽早给予患者广谱抗生素和类固醇治疗。一般来说,通过抗菌治疗、密切监测以及对出现喘鸣或呼吸急促的患者进行气管插管/气管切开术等选择性气道干预,预后良好。

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