Targarona Javier, Barreda Luis, Barreda Claudia
Departamento de Cirugía General del Hospital Nacional Edgardo Rebagliati Martins, Lima - Perú.
Rev Gastroenterol Peru. 2012 Jul-Sep;32(3):257-61.
The purpose of this study is to evaluate efficacy of the surgical indications in acute pancreatitis.
During the period from May 2000 to June 2009, 107 operated patients with pancreatic necrosis were treated in the Severe Acute Pancreatitis Unit of the HNERM a comparison was made by separating the patients in two groups according to the surgical indication. An analysis was carried out in order to evaluate which type of surgical indication has the best results according to age, severity of the case, return to oral intake, hospital stay, complications and mortality.
On evaluating the indication by positive puncture for detecting necrosis infection we found that 89% of the patients operated due to this indication showed infected necrosis while those operated due to the indication of "sepsis without response to the ICU treatment" only reached 51%. Surgical complications and re operations, was higher among the patients whose indication was "sepsis without response to the ICU treatment" (Indication B) in comparison with positive FNA. (Indication A) CONCLUSION: Positive fine needle aspiration is the surgical indication par excellence in acute pancreatitis with necrosis. We consider that the indication of "sepsis that do not respond for more than 72 hours to treatment in the ICU regardless that negative FNA" should not be taken into account, due to the very high percentage of sterile necrosis found at the time of surgery.
本研究旨在评估急性胰腺炎手术指征的疗效。
2000年5月至2009年6月期间,107例接受手术治疗的胰腺坏死患者在HNERM重症急性胰腺炎治疗单元接受治疗,根据手术指征将患者分为两组进行比较。进行分析以评估哪种手术指征在年龄、病情严重程度、恢复经口进食、住院时间、并发症和死亡率方面具有最佳结果。
在通过穿刺阳性检测坏死感染评估指征时,我们发现因该指征接受手术的患者中89%显示有感染性坏死,而因“对重症监护病房治疗无反应的脓毒症”指征接受手术的患者仅达到51%。与细针穿刺抽吸阳性(指征A)相比,“对重症监护病房治疗无反应的脓毒症”(指征B)患者的手术并发症和再次手术发生率更高。结论:细针穿刺抽吸阳性是急性坏死性胰腺炎的卓越手术指征。我们认为,“在重症监护病房治疗72小时以上无反应的脓毒症,无论细针穿刺抽吸结果为阴性”这一指征不应被考虑,因为手术时发现无菌性坏死的比例非常高。