从挪威一家大学医院血培养阳性的患者中分离到的甲氧西林敏感金黄色葡萄球菌的分子特征。
Molecular characterization of methicillin-sensitive Staphylococcus aureus isolates from bacteremic patients in a Norwegian University Hospital.
机构信息
Department of Microbiology and Infection Control, Akershus University Hospital, Lørenskog, Norway.
出版信息
J Clin Microbiol. 2013 Jan;51(1):345-7. doi: 10.1128/JCM.02571-12. Epub 2012 Nov 7.
Abstract
Staphylococcus aureus bacteremia is common in both nosocomial and community settings, and the pathogenicity of the microbe depends upon a large repertoire of virulence factors. S. aureus bacteremia isolates (n = 126) were characterized using DNA microarrays. Clonal complexes 5, 8, 15, 30, and 45 accounted for 74.6% of the isolates. We identified geographical differences in dominating clones and toxin gene profiles. One isolate was methicillin resistant. Potential associations between age and genotype were detected.
摘要
金黄色葡萄球菌菌血症在医院和社区环境中都很常见，该微生物的致病性取决于大量的毒力因子。使用 DNA 微阵列对金黄色葡萄球菌菌血症分离株（n = 126）进行了特征描述。克隆复合体 5、8、15、30 和 45 占分离株的 74.6%。我们发现了在主导克隆和毒素基因谱方面存在地理差异。有一个分离株对甲氧西林耐药。检测到年龄和基因型之间存在潜在的关联。
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