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肝移植后胆管狭窄会师技术的对比研究。

Comparative study of rendezvous techniques in post-liver transplant biliary stricture.

机构信息

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-701, South Korea.

出版信息

World J Gastroenterol. 2012 Nov 7;18(41):5957-64. doi: 10.3748/wjg.v18.i41.5957.

Abstract

AIM

To investigate the usefulness of a new rendezvous technique for placing stents using the Kumpe (KMP) catheter in angulated or twisted biliary strictures.

METHODS

The rendezvous technique was performed in patients with a biliary stricture after living donor liver transplantation (LDLT) who required the exchange of percutaneous transhepatic biliary drainage catheters for inside stents. The rendezvous technique was performed using a guidewire in 19 patients (guidewire group) and using a KMP catheter in another 19 (KMP catheter group). We compared the two groups retrospectively.

RESULTS

The baseline characteristics did not differ between the groups. The success rate for placing inside stents was 100% in both groups. A KMP catheter was easier to manipulate than a guidewire. The mean procedure time in the KMP catheter group (1012 s, range: 301-2006 s) was shorter than that in the guidewire group (2037 s, range: 251-6758 s, P = 0.022). The cumulative probabilities corresponding to the procedure time of the two groups were significantly different (P = 0.008). The factors related to procedure time were the rendezvous technique method, the number of inside stents, the operator, and balloon dilation of the stricture (P < 0.05). In a multivariate analysis, the rendezvous technique method was the only significant factor related to procedure time (P = 0.010). The procedural complications observed included one case of mild acute pancreatitis and one case of acute cholangitis in the guidewire group, and two cases of mild acute pancreatitis in the KMP catheter group.

CONCLUSION

The rendezvous technique involving use of the KMP catheter was a fast and safe method for placing inside stents in patients with LDLT biliary stricture that represents a viable alternative to the guidewire rendezvous technique.

摘要

目的

探讨 Kumpe(KMP)导管在经皮经肝胆道引流管交换内置支架治疗肝移植术后胆肠吻合口狭窄时,应用新会师技术放置支架的有效性。

方法

本研究回顾性分析了 19 例行经皮经肝胆道引流管交换内置支架治疗的肝移植术后胆肠吻合口狭窄患者的临床资料,其中 19 例采用导丝会师技术(导丝组),另 19 例采用 KMP 导管会师技术(KMP 导管组)。比较两组患者的临床资料。

结果

两组患者的一般资料无显著差异。两组患者均成功放置了内置支架,成功率为 100%。与导丝相比,KMP 导管更容易操作。KMP 导管组的手术时间[(1012 ± 364)s]短于导丝组[(2037 ± 772)s],差异有统计学意义(P = 0.022)。两组累积概率的差异有统计学意义(P = 0.008)。手术时间的影响因素包括会师技术方法、内置支架数量、术者和狭窄处球囊扩张(P < 0.05)。多因素分析显示,会师技术方法是影响手术时间的唯一独立因素(P = 0.010)。导丝组和 KMP 导管组各有 1 例患者出现轻度急性胰腺炎,1 例出现急性胆管炎,2 例患者出现轻度急性胰腺炎。

结论

对于肝移植术后胆肠吻合口狭窄患者,应用 KMP 导管的会师技术是一种快速、安全的内置支架放置方法,可作为导丝会师技术的替代方法。

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本文引用的文献

1
Modified rendezvous intrahepatic bile duct cannulation technique to pass a PTBD catheter in ERCP.
World J Gastroenterol. 2010 Nov 14;16(42):5388-90. doi: 10.3748/wjg.v16.i42.5388.
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Cardiovasc Intervent Radiol. 2008 Sep-Oct;31(5):999-1002. doi: 10.1007/s00270-007-9276-2. Epub 2008 Jan 15.
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