Kurasawa T
Kekkaku. 1990 Jan;65(1):47-52.
The maximum diameter of redness of tuberculin skin test (PPD) was studied in patients with active pulmonary tuberculosis (TB) (257 cases) and with various non-tuberculous pulmonary disorders (Non-TB) (328 cases). Negative rate of PPD (maximum diameter under 9 mm) was 9.3% in patients of TB; 6.5% in patients without underlying disorders and 16.3% with underlying disorders, which may affect the break-down of tuberculosis. In patients with miliary tuberculosis, the negative rate was high and PPD reaction became weaker in advanced patients and patients with pleurisy. High age, hypoalbminemia and lymphocytepenia in peripheral blood were the factors influencing the negative conversion of PPD skin test. In Non-TB patients, positive rate of PPD was similar between patients with and without past history of tuberculosis and the rate of patients with maximum redness over 35mm were about 10%, regardless of sex, age and disorders. But there was a difference in the positive rates of PPD between male and female; the positive rate of PPD skin test was highest in male with lung cancer, and there was a difference in the positive rate of PPD between the age groups in male, but there was no difference in females regardless of age with or without lung cancer.
对257例活动性肺结核（TB）患者和328例各种非结核性肺部疾病（非TB）患者的结核菌素皮肤试验（PPD）红晕最大直径进行了研究。TB患者中PPD阴性率（最大直径小于9mm）为9.3%；无基础疾病患者为6.5%，有基础疾病患者为16.3%，基础疾病可能影响结核杆菌的分解。粟粒性肺结核患者阴性率较高，晚期患者及胸膜炎患者PPD反应较弱。高龄、低白蛋白血症及外周血淋巴细胞减少是影响PPD皮肤试验阴性转化的因素。在非TB患者中，有或无结核病史患者的PPD阳性率相似，无论性别、年龄和疾病如何，最大红晕超过35mm的患者比例约为10%。但男女之间PPD阳性率存在差异；男性肺癌患者PPD皮肤试验阳性率最高，男性不同年龄组之间PPD阳性率存在差异，但女性无论年龄有无肺癌均无差异。
