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耐甲氧西林金黄色葡萄球菌菌血症重症患者的万古霉素最小抑菌浓度对死亡率的影响。

Impact of vancomycin minimum inhibitory concentration on mortality among critically ill patients with methicillin-resistant Staphylococcus aureus bacteremia.

机构信息

Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC 20010, USA.

出版信息

Infect Control Hosp Epidemiol. 2012 Dec;33(12):1246-9. doi: 10.1086/668433. Epub 2012 Oct 23.

Abstract

We retrospectively evaluated 99 intensive care unit patients with methicillin-resistant Staphylococcus aureus bacteremia to determine whether having a vancomycin minimum inhibitory concentration (MIC) of 2 mg/L affected mortality. This MIC was found in 5.1% of patients and was associated with the probability of death (adjusted odds ratio, 13.9 [95% confidence interval, 1.1-171.2]) independent of other factors.

摘要

我们回顾性评估了 99 例耐甲氧西林金黄色葡萄球菌菌血症的重症监护病房患者,以确定万古霉素最低抑菌浓度(MIC)为 2mg/L 是否会影响死亡率。在 5.1%的患者中发现了这种 MIC,且与死亡概率相关(校正比值比,13.9[95%置信区间,1.1-171.2]),独立于其他因素。

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