Rogozea R, Florea-Ciocoiu V
Institute of Neurology and Psychiatry, Bucharest, Romania.
Pavlov J Biol Sci. 1990 Jan-Mar;25(1):1-13. doi: 10.1007/BF02999809.
A polygraphic study on resistance to habituation of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration) and EEG (acoustic-evoked potential and EEG-blocking reaction) components of the orienting reaction, elicited by a repetitive auditory stimulus during successive (weekly) sessions was performed in 67 chronic alcoholics and in 70 matched normal subjects (control group). The study showed significant retention disturbances of orienting reaction habituation (i.e., of learning), or the "saving" of stimulations, achieved from one session to the other to obtain the habituation criterion, the savings being less in alcoholics than in control subjects. The severity of habituation retention disturbances depended on patients' ages, types of alcoholism, alcohol consumption intensity and chronicity, as well as the type of resting EEG.
对67名慢性酒精中毒者和70名匹配的正常受试者（对照组）进行了一项多导睡眠图研究，该研究通过在连续（每周一次）的实验环节中重复听觉刺激来引发定向反应，涉及躯体（肌电图）、自主神经（手指体积描记图、皮肤电反应、呼吸）和脑电图（听觉诱发电位和脑电图阻断反应）等方面。研究表明，定向反应习惯化（即学习）存在显著的保持障碍，或者说从一个实验环节到另一个环节为达到习惯化标准而获得的刺激“节省量”存在差异，酒精中毒者的节省量比对照组受试者少。习惯化保持障碍的严重程度取决于患者的年龄、酒精中毒类型、饮酒强度和慢性程度，以及静息脑电图的类型。
