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低钾血症:常见但并非总是良性。因类癌肿瘤异位分泌促肾上腺皮质激素导致的严重、持续性低钾血症。

Hypokalaemia: common but not always benign. Severe, persistent hypokalaemia secondary to ectopic ACTH from a carcinoid tumour.

作者信息

Mahmood Muhammad Muzaffar, John Kurien

机构信息

Department of Cardiology, Sunderland Royal Hospital, Sunderland, UK.

出版信息

BMJ Case Rep. 2012 Nov 14;2012:bcr-2012-007193. doi: 10.1136/bcr-2012-007193.

Abstract

Hypokalaemia is a common and often benign observation. There is usually an obvious underlying cause for the anomaly. However, hypokalaemia can very rarely be the sole presentation of a more sinister disease. A high index of suspicion and a systematic approach are therefore required to avoid delays in the management, especially in the context of presentation to a medical team. We present a case of a patient with severe and persistent hypokalaemia due to ectopic adrenocorticotropic hormone (ACTH) secretion secondary to a carcinoid tumour. The case report is followed by a brief discussion on the approach to the management of hypokalaemia and additional tests to confirm ectopic ACTH.

摘要

低钾血症是一种常见且通常为良性的表现。这种异常情况通常有明显的潜在病因。然而,低钾血症极少会是更严重疾病的唯一表现。因此,需要高度的怀疑指数和系统的方法来避免治疗延误,尤其是在向医疗团队就诊的情况下。我们报告一例因类癌肿瘤分泌异位促肾上腺皮质激素(ACTH)导致严重持续性低钾血症的患者。病例报告之后是关于低钾血症治疗方法及确认异位ACTH的其他检查的简要讨论。

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