Imai Keiko, Kayashima Kenji, Yoshino Hiroomi, Kinoshita Yuki
Department of Anesthesia, Kyushukoseinenkin Hospital Kitakyushu 806-8511.
Masui. 2012 Oct;61(10):1091-4.
Incident rates of cardiac arrest are reported as being from 0.54 to 17.5 per 10,000 (0.54-17.5/10,000) spinal anesthesia patients. In our hospital, four cases of cardiac arrest occurred in 903 spinal and combined spinal and epidural anesthesia patients over 15 months (44.3/ 10,000). Common denominators were ages below 60 years, ASA-PS 1, rapid onset of T10 blockade within 2 minutes and leg raising from 3 to 6 minutes after administration of hyperbaric bupivacaine and T4 blockade. All patients recovered without any side effects. The conditions suspected of causing strong bradycardia leading to cardiac arrest are thought to be maintained parasympathetic activity, lack of blood volume before anesthesia, rapid progress of spinal blockade, decreased blood return to the heart by high spinal blockade (T4) and protective cardiac parasympathetic reflex (Bezold-Jarisch reflex).
据报道,脊髓麻醉患者心脏骤停的发生率为每10000例中有0.54至17.5例(0.54 - 17.5/10000)。在我们医院,903例接受脊髓麻醉和腰麻 - 硬膜外联合麻醉的患者在15个月内发生了4例心脏骤停(44.3/10000)。共同特征为年龄低于60岁、美国麻醉医师协会身体状况分级(ASA - PS)为1级、在2分钟内T10阻滞迅速起效、在给予高压布比卡因后3至6分钟出现下肢抬高以及T4阻滞。所有患者均康复且无任何副作用。被怀疑导致严重心动过缓进而引起心脏骤停的情况被认为是副交感神经活动持续存在、麻醉前血容量不足、脊髓阻滞进展迅速、高位脊髓阻滞(T4)导致回心血量减少以及心脏保护性副交感反射(贝佐尔德 - 雅里什反射)。