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一例以急性心肌炎为首发表现的克罗恩病。

A case of acute myocarditis as the initial presentation of Crohn's disease.

机构信息

Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

出版信息

Gut Liver. 2012 Oct;6(4):512-5. doi: 10.5009/gnl.2012.6.4.512. Epub 2012 Oct 18.

Abstract

We experienced a case of acute myocarditis as the initial presentation of Crohn's disease. A 19-year-old woman was admitted with impaired consciousness, shock, and respiratory failure. She had suffered from frequent diarrhea and abdominal pain for several years. Cardiac troponin I and creatine kinase-MB fraction levels were elevated to 5.32 and 16.66 ng/mL, respectively. A 12-lead electrocardiogram showed sinus tachycardia, and a chest radiograph revealed interstitial pulmonary edema. An echocardiogram showed dilated ventricles with akinesia of the basal to apical inferoseptal, anteroseptal, anterior, and inferior left ventricular walls and severely impaired systolic function. Intensive care with inotropic support was effective, and her clinical condition gradually improved. Two weeks later, a colonoscopy revealed ulceration with stenosis in the terminal ileum and multiple aphthous ulcers in the rectum. A biopsy of the rectum revealed non-caseating granulomatous inflammation. She was diagnosed with Crohn's disease presenting with acute myocarditis.

摘要

我们遇到了一例以急性心肌炎为首发表现的克罗恩病。一名 19 岁女性因意识障碍、休克和呼吸衰竭入院。她经常腹泻和腹痛已有数年。心肌肌钙蛋白 I 和肌酸激酶-MB 同工酶水平分别升高至 5.32 和 16.66ng/ml。12 导联心电图显示窦性心动过速,胸片显示间质性肺水肿。超声心动图显示心室扩张,基底至心尖下间隔、前间隔、前壁和下壁左心室壁运动障碍,收缩功能严重受损。给予正性肌力支持的重症监护有效,她的临床状况逐渐改善。两周后,结肠镜检查显示末端回肠溃疡伴狭窄和直肠多发性口疮样溃疡。直肠活检显示非干酪性肉芽肿性炎症。她被诊断为以急性心肌炎为首发表现的克罗恩病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec0/3493735/d0033b285f31/gnl-6-512-g001.jpg

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