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左心室动脉瘤手术治疗后的早期结果。

Early results after surgical treatment of left ventricular aneurysm.

作者信息

Wang Xisheng, He Xuezhi, Mei Yunqing, Ji Qiang, Feng Jing, Cai Jianzhi, Sun Yifeng, Xie Shiliang

机构信息

The Department of Thoracic Cardiovascular Surgery, Tongji Hospital of Tongji University, 389 Xincun Road, Shanghai, 200065, China.

出版信息

J Cardiothorac Surg. 2012 Nov 21;7:126. doi: 10.1186/1749-8090-7-126.

Abstract

BACKGROUND

Left ventricular aneurysm (LVA) is a serious complication of myocardial infarction and reduces the chances of survival. Controversy still exists regarding the optimal surgical technique for LVA repair. We analyze the efficacy of two techniques, linear vs. endoventricular circular patch plasty, for repair of LVA and the efficacy of surgical ventricular restoration (SVR) on beating heart.

METHODS

This study included 62 patients who underwent SVR from 1086 consecutive patients were subjected to coronary artery bypass grafting (CABG) between 2000 and 2009. All selected patients were divided either into group liner or patch according to the choice of the repair technique depended on factors such as localization, size and dimension of the scar. The patients also were divided either into group beating heart or cardioplegia. The pre-, intra- and postoperative relevant data of all selected patients were analyzed.

RESULTS

The mortality was not significantly different between linear and patch repair groups, also the actuarial survival rates within 24 months (p= 0.529). Postoperative echocardiographic findings showed significant improvements in left ventricular function in both groups. The beating heart technique reduced postoperative peak release by 27% for Cardiac troponin I (cTnI) compared with the cardioplegia group (0.46 ± 0.06 ng/mL versus 0.63 ± 0.09 ng/mL, p= 0.004), and increased the perioperative survival by 9% (97.2% versus 88.5%), but the actuarial survival rates were not significantly different between the groups from 2 to 24 months (p= 0.151).

CONCLUSIONS

Both techniques (linear and patch) achieved good results with respect to mortality, functional status and survival. The choice of surgical technique should be adapted in each patient. The beating heart technique may to some extent relieve myocardial injury in patients undergoing SVR.

摘要

背景

左心室室壁瘤(LVA)是心肌梗死的严重并发症,会降低患者的生存几率。关于LVA修复的最佳手术技术仍存在争议。我们分析了两种技术,即线性修复与心室内环形补片修补术,用于LVA修复的疗效以及心脏不停跳手术心室修复(SVR)的疗效。

方法

本研究纳入了2000年至2009年间1086例接受冠状动脉旁路移植术(CABG)的连续患者中62例接受SVR的患者。所有入选患者根据修复技术的选择分为线性组或补片组,修复技术的选择取决于瘢痕的位置、大小和尺寸等因素。患者还分为心脏不停跳组或心脏停搏组。分析了所有入选患者术前、术中和术后的相关数据。

结果

线性修复组和补片修复组的死亡率无显著差异,24个月内的精算生存率也无显著差异(p = 0.529)。术后超声心动图检查结果显示两组左心室功能均有显著改善。与心脏停搏组相比,心脏不停跳技术使心肌肌钙蛋白I(cTnI)术后峰值释放降低了27%(0.46±0.06 ng/mL对0.63±0.09 ng/mL,p = 0.004),围手术期生存率提高了9%(97.2%对88.5%),但2至24个月时两组的精算生存率无显著差异(p = 0.151)。

结论

两种技术(线性和补片)在死亡率、功能状态和生存率方面均取得了良好效果。手术技术的选择应根据每位患者的情况进行调整。心脏不停跳技术在一定程度上可能减轻接受SVR患者的心肌损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e611/3527346/9e1a6d53d785/1749-8090-7-126-1.jpg

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